《玫瑰之名》中使用了哪种毒药?

Q4 Medicine
Tomasz Konopka
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引用次数: 1

摘要

在翁贝托·艾柯(Umberto Eco)的小说《玫瑰之名》(the Name of the Rose)中,一个狂热的僧侣在一本书的书页上涂上了毒药,导致一座中世纪修道院的几名僧侣死亡。根据现代毒理学知识,可以尝试确定是否存在符合小说中描述的毒物标准的物质。为此,对有关植物源毒物致死剂量及其作用时间的毒理学文献进行了综述。牛膝草(Cicuta virosa),一种用于制作有毒药剂的植物,含有500毫克的毒毒素,可致人死亡。生长在印度和马达加斯加的水草(Oenanthe crocata)和木耳(Cerbera odolam)也表现出类似的毒性。铁杉(Conium maculatum)含有可毒碱,在接触低至100至200毫克的剂量后就能杀死受害者。罂粟(Papaver somniferum)中含有的吗啡和秋藏红花(Colchicum autumn)中含有的秋水仙碱在相同的剂量下会产生致命的效果。也有更多的外来植物,如卡拉巴豆(physo柱头venenosum),其中含有physostygine。在这里需要提到的另外两种外来植物的毒性要大得多。它们包括圣依纳爵豆(Strychnos ignatii)和士的宁树(Strychnos nux-vomica)。两者都含有士的宁,致死剂量为30毫克。在这种情况下,也可以考虑死亡帽(Amanita phalloides),但尽管这种真菌中含有的amanitin在20毫克的剂量下是致命的,但它需要几天的时间才能杀死受害者,所以效果比艾柯小说中僧侣所经历的要慢得多。10毫克的剂量足以与其他四种植物衍生毒物中的任何一种一起致死:antiarin, atropine,地高辛和strophantin。乌头(Aconitum napellus),也被称为乌头,含有乌头碱,是一种更致命的植物,对人类的致命剂量只有2毫克。蓖麻毒素和蓖麻毒素在植物源毒素中排名更高,因为它们的致死剂量低于1毫克。然而,在《玫瑰之名》中,凶手不可能使用它们,因为它们在摄入后几天就会导致死亡。总之,最符合小说中提到的标准的植物是乌头。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
What kind of poison was used in "The Name of the Rose"?

In the novel "The Name of the Rose" by Umberto Eco, a fanatical monk laced the pages of a book with a poison, which led to the death of several monks in a medieval monastery. Based on modern toxicological knowledge, an attempt can be made to determine whether there exists a substance meeting the criteria of the poison described in the novel. To this end, toxicological literature on the lethal doses of plant-derived poisons and their duration of action was reviewed. Cowbane (Cicuta virosa), a plant used for preparing poisonous potions, contains cicutoxin which kills at a dose of 500 mg. Similar toxicity is displayed by water dropwort (Oenanthe crocata) and Cerbera odollam growing in India and Madagascar. Hemlock (Conium maculatum) contains coniine which is able to kill a victim after exposure to a dose as low as 100 to 200 mg. Morphine found in opium poppy (Papaver somniferum) and colchicine contained in autumn crocus (Colchicum autumnale) produce lethal effects at similar doses. So do more exotic plants such as Calabar bean (Physostigma venenosum) which contains physostygmine. Two other exotic plants that need to be mentioned in this context are far more poisonous. They include Saint Ignatius's bean (Strychnos ignatii) and strychnine tree (Strychnos nux-vomica). Both contain strychnine, the lethal dose of which is 30 mg. Death cap (Amanita phalloides) might also be considered in this context, but despite being lethal at a dose of 20 mg, amanitin contained in this fungus takes a few days to kill a victim, so the effect is considerably slower than that experienced by the monks in Eco's novel. A dose of 10 mg is sufficient to kill a human with any of four other plant-derived poisons: antiarin, atropine, digoxin and strophantin. Aconitum (Aconitum napellus), also known as monkshood, contains aconitine and is an even more deadly plant, with the lethal dose for humans being only 2 mg. Ricin and abrin are ranked even higher in the list of plant-derived toxins, as they are able to kill in doses lower than 1 mg. However, they could not have been used by the murderer in "The Name of the Rose", as they cause death only several days after ingestion. To conclude, the plant that best matches the criteria mentioned in the novel is Aconitum.

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来源期刊
CiteScore
0.60
自引率
0.00%
发文量
12
审稿时长
12 weeks
期刊介绍: Archiwum Medycyny Sądowej i Kryminologii przyjmuje w języku polskim: prace doświadczalne, poglądowe, kazuistyczne, artykuły o charakterze szkoleniowym z medycyny sądowej, kryminologii i dziedzin pokrewnych, opracowania z zakresu etyki i deontologii lekarskiej, streszczenia prac obcych, oceny książek, sprawozdania z działalności PTMSiK, sprawozdania ze zjazdów krajowych i zagranicznych, komunikaty Zarządu Głównego PTMSiK, listy do Redakcji. Autor powinien podać, do jakiej kategorii zalicza tekst nadesłanej pracy. Przyjmowane do druku będą również prace autorów zagranicznych w języku angielskim.
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