冠状病毒病2019 (COVID-19)的急诊心脏成像实践:takotsubo应激性心肌病1例

IF 1.9 3区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Oriana Belli, Maddalena Ardissino, Maurizio Bottiroli, Francesco Soriano, Calogero Blanda, Jacopo Oreglia, Michele Mondino, Antonella Moreo
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引用次数: 4

摘要

背景:已知严重急性呼吸窘迫综合征冠状病毒2 (SARS-CoV2)的心血管并发症与不良预后相关。少数病例系列和报告描述了心肌炎和缺血性事件的病例,然而,关于SARS-CoV2急性心力衰竭的病因学知识仍然有限。我们描述了重症监护病房2019冠状病毒病(COVID-19)患者出现的“takotsubo”应激性心肌病的发生和风险分层成像相关因素。1例53岁经气管插管的新冠肺炎患者在重症监护室出现急性血流动力学衰竭,经胸超声心动图(TTE)、12导联心电图(ECG)及一系列肌钙蛋白和血液检查,最终因临床怀疑缺血性病因而进行冠状动脉造影。超声心动图显示射血分数降低,伴有明显的广泛的冠状动脉运动障碍。肌钙蛋白和NT-proBNP升高,心电图显示ST段升高:因此进行冠状动脉造影。这显示没有明显的冠状动脉狭窄。在接下来的一周内复查超声心动图显示射血分数和壁运动异常明显恢复。尽管需要延长ICU的住院时间,但患者目前临床稳定,并自主呼吸。结论:本病例报告发生在重症监护室的1例covid - 19危重症患者的应激性心肌病。应激性心肌病可能是COVID-19感染的急性心血管并发症。在covid - 19重症监护环境中,紧急床边超声心动图是对血流动力学受损患者进行初步临床评估的重要工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Emergency cardiac imaging for coronavirus disease 2019 (COVID-19) in practice: a case of takotsubo stress cardiomyopathy.

Background: Cardiovascular complications of severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV2) are known to be associated with poor outcome. A small number of case series and reports have described cases of myocarditis and ischaemic events, however, knowledge on the aetiology of acute cardiac failure in SARS-CoV2 remains limited. We describe the occurrence and risk stratification imaging correlates of 'takotsubo' stress cardiomyopathy presenting in a patient with Coronavirus Disease 2019 (COVID-19) in the intensive care unit. An intubated 53-year old patient with COVID19 suffered acute haemodynamic collapse in the intensive care unit, and was thus investigated with transthoracic echocardiography (TTE), 12-lead electrocardiograms (ECG) and serial troponins and blood tests, and eventually coronary angiography due to clinical suspicion of ischaemic aetiology. Echocardiography revealed a reduced ejection fraction, with evident extensive apical akinesia spanning multiple coronary territories. Troponins and NT-proBNP were elevated, and ECG revealed ST elevation: coronary angiography was thus performed. This revealed no significant coronary stenosis. Repeat echocardiography performed within the following week revealed a substantial recovery of ejection fraction and wall motion abnormalities. Despite requirement of a prolonged ICU stay, the patient now remains clinically stable, and is on spontaneous breathing.

Conclusion: This case report presents a case of takotsubo stress cardiomyopathy occurring in a critically unwell patient with COVID19 in the intensive care setting. Stress cardiomyopathy may be an acute cardiovascular complication of COVID-19 infection. In the COVID19 critical care setting, urgent bedside echocardiography is an important tool for initial clinical assessment of patients suffering haemodynamic compromise.

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来源期刊
Cardiovascular Ultrasound
Cardiovascular Ultrasound CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
4.10
自引率
0.00%
发文量
28
审稿时长
>12 weeks
期刊介绍: Cardiovascular Ultrasound is an online journal, publishing peer-reviewed: original research; authoritative reviews; case reports on challenging and/or unusual diagnostic aspects; and expert opinions on new techniques and technologies. We are particularly interested in articles that include relevant images or video files, which provide an additional dimension to published articles and enhance understanding. As an open access journal, Cardiovascular Ultrasound ensures high visibility for authors in addition to providing an up-to-date and freely available resource for the community. The journal welcomes discussion, and provides a forum for publishing opinion and debate ranging from biology to engineering to clinical echocardiography, with both speed and versatility.
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