68Ga-FAPI PET/CT胸腺鳞状细胞癌模拟淋巴瘤。

IF 1 4区医学 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Nuklearmedizin-nuclear Medicine Pub Date : 2021-12-01 Epub Date: 2021-08-17 DOI:10.1055/a-1561-2014

Xiao Yang, Zhouxiang You, Yue Chen, Tianyang Dai, Huipan Liu

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Thymic squamous cell carcinoma mimicking lymphoma on 68Ga-FAPI PET/CT.

A 33-year-old man presented with progressive enlargement of supraclavicular fossa mass for 2 years. Recently, the patient feels neck pain when swallowing food. Previous chest CT imaging revealed an anterior mediastinal soft tissue mass without any evidence for adjacent vascular or lung invasion (approximately 4.1 cm × 3.4 cm in size), indicating a mediastinal tumor; therefore, malignancy could not be ruled out. With the consent of the patient, we enrolled him in a clinical trial of 68Ga-FAPI-04 PET/CT in tumors (ChiCTR2100044131). 68Ga-FAPI-04 PET/CT scan (▶ Fig. 1A-D) detected that the anterior mediastinal mass had intense FAPI uptake (SUVmax of 12.0). Based on these PET/CT findings, the lesion was suspected to be a mediastinal lymphoma. Subsequently, the patient underwent surgical resection of soft tissue mass. Immunohistochemistry revealed CK (+), CK19 (+), P63 (+), CD1a (+), TdT (+), CD5 (+), CD20 (+), CD117 (+), P53 (+, 50 %), Ki-67 (+, 40 %). However, the findings were consistent with thymic squamous cell carcinoma (SCC). Finally, the patient was well at the six-month follow-up visit.

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来源期刊

Nuklearmedizin-nuclear Medicine 医学-核医学

CiteScore

1.70

自引率

13.30%

发文量

267

审稿时长

>12 weeks

期刊介绍： Als Standes- und Fachorgan (Organ von Deutscher Gesellschaft für Nuklearmedizin (DGN), Österreichischer Gesellschaft für Nuklearmedizin und Molekulare Bildgebung (ÖGN), Schweizerischer Gesellschaft für Nuklearmedizin (SGNM, SSNM)) von hohem wissenschaftlichen Anspruch befasst sich die CME-zertifizierte Nuklearmedizin/ NuclearMedicine mit Diagnostik und Therapie in der Nuklearmedizin und dem Strahlenschutz: Originalien, Übersichtsarbeiten, Referate und Kongressberichte stellen aktuelle Themen der Diagnose und Therapie dar. Ausführliche Berichte aus den DGN-Arbeitskreisen, Nachrichten aus Forschung und Industrie sowie Beschreibungen innovativer technischer Geräte, Einrichtungen und Systeme runden das Konzept ab. Die Abstracts der Jahrestagungen dreier europäischer Fachgesellschaften sind Bestandteil der Kongressausgaben. Nuklearmedizin erscheint regelmäßig mit sechs Ausgaben pro Jahr und richtet sich vor allem an Nuklearmediziner, Radiologen, Strahlentherapeuten, Medizinphysiker und Radiopharmazeuten.