Scott M Stevens, Scott C Woller, Lisa Baumann Kreuziger, Henri Bounameaux, Kevin Doerschug, Geert-Jan Geersing, Menno V Huisman, Clive Kearon, Christopher S King, Andrew J Knighton, Erica Lake, Susan Murin, Janine R E Vintch, Philip S Wells, Lisa K Moores
{"title":"静脉血栓栓塞疾病的抗血栓治疗:胸部指南和专家小组报告的第二次更新。","authors":"Scott M Stevens, Scott C Woller, Lisa Baumann Kreuziger, Henri Bounameaux, Kevin Doerschug, Geert-Jan Geersing, Menno V Huisman, Clive Kearon, Christopher S King, Andrew J Knighton, Erica Lake, Susan Murin, Janine R E Vintch, Philip S Wells, Lisa K Moores","doi":"10.1016/j.chest.2021.07.055","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>This is the 2nd update to the 9th edition of these guidelines. We provide recommendations on 17 PICO (Population, Intervention, Comparator, Outcome) questions, four of which have not been addressed previously.</p><p><strong>Methods: </strong>We generate strong and weak recommendations based on high-, moderate-, and low-certainty evidence, using GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) methodology.</p><p><strong>Results: </strong>The panel generated 29 guidance statements, 13 of which are graded as strong recommendations, covering aspects of antithrombotic management of VTE from initial management through secondary prevention and risk reduction of postthrombotic syndrome. Four new guidance statements have been added that did not appear in the 9th edition (2012) or 1st update (2016). Eight statements have been substantially modified from the 1st update.</p><p><strong>Conclusion: </strong>New evidence has emerged since 2016 that further informs the standard of care for patients with VTE. Substantial uncertainty remains regarding important management questions, particularly in limited disease and special patient populations.</p>","PeriodicalId":9,"journal":{"name":"ACS Catalysis ","volume":" ","pages":"e545-e608"},"PeriodicalIF":11.3000,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"329","resultStr":"{\"title\":\"Antithrombotic Therapy for VTE Disease: Second Update of the CHEST Guideline and Expert Panel Report.\",\"authors\":\"Scott M Stevens, Scott C Woller, Lisa Baumann Kreuziger, Henri Bounameaux, Kevin Doerschug, Geert-Jan Geersing, Menno V Huisman, Clive Kearon, Christopher S King, Andrew J Knighton, Erica Lake, Susan Murin, Janine R E Vintch, Philip S Wells, Lisa K Moores\",\"doi\":\"10.1016/j.chest.2021.07.055\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>This is the 2nd update to the 9th edition of these guidelines. We provide recommendations on 17 PICO (Population, Intervention, Comparator, Outcome) questions, four of which have not been addressed previously.</p><p><strong>Methods: </strong>We generate strong and weak recommendations based on high-, moderate-, and low-certainty evidence, using GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) methodology.</p><p><strong>Results: </strong>The panel generated 29 guidance statements, 13 of which are graded as strong recommendations, covering aspects of antithrombotic management of VTE from initial management through secondary prevention and risk reduction of postthrombotic syndrome. Four new guidance statements have been added that did not appear in the 9th edition (2012) or 1st update (2016). Eight statements have been substantially modified from the 1st update.</p><p><strong>Conclusion: </strong>New evidence has emerged since 2016 that further informs the standard of care for patients with VTE. Substantial uncertainty remains regarding important management questions, particularly in limited disease and special patient populations.</p>\",\"PeriodicalId\":9,\"journal\":{\"name\":\"ACS Catalysis \",\"volume\":\" \",\"pages\":\"e545-e608\"},\"PeriodicalIF\":11.3000,\"publicationDate\":\"2021-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"329\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Catalysis \",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.chest.2021.07.055\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2021/8/2 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, PHYSICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Catalysis ","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.chest.2021.07.055","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/8/2 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
Antithrombotic Therapy for VTE Disease: Second Update of the CHEST Guideline and Expert Panel Report.
Background: This is the 2nd update to the 9th edition of these guidelines. We provide recommendations on 17 PICO (Population, Intervention, Comparator, Outcome) questions, four of which have not been addressed previously.
Methods: We generate strong and weak recommendations based on high-, moderate-, and low-certainty evidence, using GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) methodology.
Results: The panel generated 29 guidance statements, 13 of which are graded as strong recommendations, covering aspects of antithrombotic management of VTE from initial management through secondary prevention and risk reduction of postthrombotic syndrome. Four new guidance statements have been added that did not appear in the 9th edition (2012) or 1st update (2016). Eight statements have been substantially modified from the 1st update.
Conclusion: New evidence has emerged since 2016 that further informs the standard of care for patients with VTE. Substantial uncertainty remains regarding important management questions, particularly in limited disease and special patient populations.
期刊介绍：
ACS Catalysis is an esteemed journal that publishes original research in the fields of heterogeneous catalysis, molecular catalysis, and biocatalysis. It offers broad coverage across diverse areas such as life sciences, organometallics and synthesis, photochemistry and electrochemistry, drug discovery and synthesis, materials science, environmental protection, polymer discovery and synthesis, and energy and fuels.
The scope of the journal is to showcase innovative work in various aspects of catalysis. This includes new reactions and novel synthetic approaches utilizing known catalysts, the discovery or modification of new catalysts, elucidation of catalytic mechanisms through cutting-edge investigations, practical enhancements of existing processes, as well as conceptual advances in the field. Contributions to ACS Catalysis can encompass both experimental and theoretical research focused on catalytic molecules, macromolecules, and materials that exhibit catalytic turnover.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
