由不同表面活性剂组成的非抗菌和抗菌ZnO纳米颗粒。

Journal of nanoscience and nanotechnology Pub Date : 2021-12-01 DOI:10.1166/jnn.2021.19513

Saee Gharpure, Tushar Jadhav, Chetan Ghotekar, Anuja Jagtap, Yogita Vare, Balaprasad Ankamwar

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引用次数: 3

摘要

采用SDS、CTAB、Triton X-100、PVP K-30和乙二醇等不同表面活性剂合成氧化锌纳米颗粒。研究了氧化锌纳米粒子焙烧前后对大肠杆菌、铜绿假单胞菌(革兰氏阴性)以及金黄色葡萄球菌和枯草芽孢杆菌(革兰氏阳性)等不同微生物的抑菌活性。sdscapdzno NPs仅对枯草芽孢杆菌具有抑菌活性。在0.625 ~ 10 mg/mL的浓度范围内测定zno包盖SDS的抑菌活性。与煅烧后相比，煅烧前的抗菌活性增加。未焙烧和焙烧SDS-capped ZnO NPs的最低抑菌浓度分别为2.5 mg/mL和5 mg/mL。ZnO NPs的非抗菌特性突出了其在药物传递方面的进一步应用，因为它具有惰性性质，与治疗药物结合的功效增强以及易于处理。

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Non-Antibacterial and Antibacterial ZnO Nanoparticles Composed of Different Surfactants.

Zinc oxide nanoparticles were synthesized using different surfactants such as SDS, CTAB, Triton X-100, PVP K-30 and ethylene glycol. ZnO NPs were tested for antibacterial activity before and after calcination against different micro-organisms like E. coli and P. aeruginosa (Gram negative) as well as S. aureus and B. subtilis (Gram positive). Antibacterial activity was observed in SDScapped ZnO NPs only against B. subtilis. Antibacterial activity of ZnO-capped SDS was tested in a concentration range 0.625-10 mg/mL. Increased antibacterial activity was observed before calcination as compared to after calcination. Minimum concentration at which uncalcinated as well as calcinated SDS-capped ZnO NPs show antibacterial activity is 2.5 mg/mL and 5 mg/mL respectively. Non-antibacterial nature of ZnO NPs highlights its further use in drug delivery due to its inert nature, enhanced efficacy in association with therapeutic drugs as well as easy disposal.

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来源期刊

Journal of nanoscience and nanotechnology 工程技术-材料科学：综合

自引率

0.00%

发文量

审稿时长

3.6 months

期刊介绍： JNN is a multidisciplinary peer-reviewed journal covering fundamental and applied research in all disciplines of science, engineering and medicine. JNN publishes all aspects of nanoscale science and technology dealing with materials synthesis, processing, nanofabrication, nanoprobes, spectroscopy, properties, biological systems, nanostructures, theory and computation, nanoelectronics, nano-optics, nano-mechanics, nanodevices, nanobiotechnology, nanomedicine, nanotoxicology.