喀麦隆复发性缺血性和出血性中风:一项病例对照研究。

IF 1.7 Q4 NEUROSCIENCES
Neurology Research International Pub Date : 2021-06-15 eCollection Date: 2021-01-01 DOI:10.1155/2021/9948990
Jaurès Kamgang, Francklin Tétinou, Yvan Zolo, Chee Yang Tan, Christian Wambo, Emerancienne J N Fongang, Ulrick Sidney Kanmounye
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引用次数: 0

摘要

卒中复发占灾难性并发症的很大比例,但尚未有全面的研究分析喀麦隆卒中复发的相关因素。我们开展这项病例对照研究是为了更好地了解与喀麦隆卒中复发相关的因素。方法:我们收集了喀麦隆雅温得中心医院神经内科和心内科就诊的符合条件的患者的社会人口学、临床、神经影像学、实验室和治疗数据。我们纳入了截至2019年1月15日咨询作者所在机构的所有距首次中风事件至少5年的患者。使用了Wilcoxon sign -rank和Fisher的精确检验。此外,采用Cox回归模型来识别混杂因素。结果:我们招募了100例患者;十分之七的患者患有高血压,而十分之六的患者有久坐不动的生活方式。一半的患者经常饮酒,而五分之一的患者患有糖尿病。大多数患者出现了第一次中风事件,四分之一的患者中风复发。中风复发与右偏手性(或= 0.23,95% CI = 0.16 - -0.33),充血性心力衰竭(或= 3.45,95% CI -10.28 = 1.16),痛风(或= 4.34,95% CI -18.09 = 1.09),构音障碍(或= 4.34,95% CI = 1.30 - -14.54),和面部麻痹(或= 3.96,95% CII = 1.49 - 10.51),以及修改的因素,如腹部围升高(P PπP P B = -1.48, P = 0.04)作为一个统计上显著的解释变量对中风复发。结论:我们绘制了喀麦隆复发性中风的景观图。有必要评估次优药物依从率的原因,以及非药物干预的作用和依从性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Recurrent Ischemic and Hemorrhagic Stroke in Cameroon: A Case-Control Study.

Recurrent Ischemic and Hemorrhagic Stroke in Cameroon: A Case-Control Study.

Introduction: Stroke recurrence accounts for a great percentage of catastrophic complications, yet no comprehensive study has analyzed the factors associated with stroke recurrence in Cameroon. We carried out this case-control study to better understand the factors associated with the stroke recurrence in Cameroon.

Methods: We collected sociodemographic, clinical, neuroimaging, laboratory, and therapeutic data of eligible patients who consulted the neurology and cardiology department of the Yaounde Central Hospital in Cameroon. We included all patients at least five years removed from their first stroke event who consulted the authors' institution as of January 15, 2019. Wilcoxon signed-rank and Fisher's exact tests were used. Also, a Cox regression model was used to identify confounders.

Results: We recruited 100 patients; seven out of ten patients had hypertension, while six out of 10 had a sedentary lifestyle. Half of the patients consumed alcohol regularly, while one patient out of five had diabetes. Most patients presented with their first stroke event, and a quarter had a stroke recurrence. Stroke recurrence was associated with right handedness (OR = 0.23, 95% CI = 0.16-0.33), congestive heart failure (OR = 3.45, 95% CI = 1.16-10.28), gout (OR = 4.34, 95% CI = 1.09-18.09), dysarthria (OR = 4.34, 95% CI = 1.30-14.54), and facial palsy (OR = 3.96, 95% CII = 1.49 - 10.51), as well as modifiable factors such as elevated abdominal circumference (P < 0.01), systolic blood pressure (P < 0.01), blood glucose level (PI P < 0.01), and triglyceride levels (P < 0.01). The mulitvariable regression model only identified laterality (B = -1.48, P = 0.04) as a statistically significant explanatory varibale for stroke recurrence.

Conclusion: We mapped the landscape of recurrent strokes in Cameroon. There is a need to evaluate the causes of suboptimal drug adherence rates and both the role and adherence to nonpharmacologic interventions.

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来源期刊
CiteScore
3.50
自引率
0.00%
发文量
10
审稿时长
17 weeks
期刊介绍: Neurology Research International is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies focusing on diseases of the nervous system, as well as normal neurological functioning. The journal will consider basic, translational, and clinical research, including animal models and clinical trials.
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