Ahmed Arafa, Xiaowen Wang, Jia-Yi Dong, Ehab S Eshak
{"title":"多发性硬化症会增加子痫前期的风险吗?系统回顾和荟萃分析。","authors":"Ahmed Arafa, Xiaowen Wang, Jia-Yi Dong, Ehab S Eshak","doi":"10.1080/10641955.2021.1921792","DOIUrl":null,"url":null,"abstract":"<p><p><b>Objective</b>: We investigated, via systematic review and meta-analysis, whether multiple sclerosis (MS) is associated with the risk of preeclampsia (PE).<b>Methods</b>: From the eligible studies, we pooled odds ratios (ORs) and confidence intervals (CIs) of PE for pregnant women with MS compared with pregnant women without it using the fixed-effects model. The <i>I</i><sup>2</sup> measured heterogeneity between studies.<b>Results</b>: Eight eligible studies (9 cohorts) were included. Pregnant women with MS had no excess risk of PE compared with pregnant women without MS (pooled OR = 0.99, 95% CI: 0.89, 1.09; <i>I</i><sup>2</sup> = 0.00%).<b>Conclusion</b>: MS is not associated with PE.</p>","PeriodicalId":13054,"journal":{"name":"Hypertension in Pregnancy","volume":"40 3","pages":"180-185"},"PeriodicalIF":1.5000,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/10641955.2021.1921792","citationCount":"1","resultStr":"{\"title\":\"Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis.\",\"authors\":\"Ahmed Arafa, Xiaowen Wang, Jia-Yi Dong, Ehab S Eshak\",\"doi\":\"10.1080/10641955.2021.1921792\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Objective</b>: We investigated, via systematic review and meta-analysis, whether multiple sclerosis (MS) is associated with the risk of preeclampsia (PE).<b>Methods</b>: From the eligible studies, we pooled odds ratios (ORs) and confidence intervals (CIs) of PE for pregnant women with MS compared with pregnant women without it using the fixed-effects model. The <i>I</i><sup>2</sup> measured heterogeneity between studies.<b>Results</b>: Eight eligible studies (9 cohorts) were included. Pregnant women with MS had no excess risk of PE compared with pregnant women without MS (pooled OR = 0.99, 95% CI: 0.89, 1.09; <i>I</i><sup>2</sup> = 0.00%).<b>Conclusion</b>: MS is not associated with PE.</p>\",\"PeriodicalId\":13054,\"journal\":{\"name\":\"Hypertension in Pregnancy\",\"volume\":\"40 3\",\"pages\":\"180-185\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2021-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1080/10641955.2021.1921792\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Hypertension in Pregnancy\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/10641955.2021.1921792\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2021/5/17 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hypertension in Pregnancy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/10641955.2021.1921792","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2021/5/17 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
Does multiple sclerosis increase the risk of preeclampsia? A systematic review and meta-analysis.
Objective: We investigated, via systematic review and meta-analysis, whether multiple sclerosis (MS) is associated with the risk of preeclampsia (PE).Methods: From the eligible studies, we pooled odds ratios (ORs) and confidence intervals (CIs) of PE for pregnant women with MS compared with pregnant women without it using the fixed-effects model. The I2 measured heterogeneity between studies.Results: Eight eligible studies (9 cohorts) were included. Pregnant women with MS had no excess risk of PE compared with pregnant women without MS (pooled OR = 0.99, 95% CI: 0.89, 1.09; I2 = 0.00%).Conclusion: MS is not associated with PE.
期刊介绍:
Hypertension in Pregnancy is a refereed journal in the English language which publishes data pertaining to human and animal hypertension during gestation. Contributions concerning physiology of circulatory control, pathophysiology, methodology, therapy or any other material relevant to the relationship between elevated blood pressure and pregnancy are acceptable. Published material includes original articles, clinical trials, solicited and unsolicited reviews, editorials, letters, and other material deemed pertinent by the editors.