蛛网膜下腔出血后急性微血栓形成:新的治疗靶点?

Fenghui Ye, Richard F Keep, Ya Hua, Hugh Jl Garton, Guohua Xi
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引用次数: 11

摘要

蛛网膜下腔出血(SAH)后脑内微血栓形成已被确认并怀疑与脑缺血有关。最近的一项研究发现,实验性SAH后4小时发生超早期脑微血栓形成。血栓性微血管的数量与脑血屏障破坏和神经元损伤相关。如果急性脑微血栓也发生在人类身上,是时候开发一种全身溶栓治疗SAH患者了吗?
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Acute micro-thrombosis after subarachnoid hemorrhage: A new therapeutic target?

Microthrombi formation in the brain following subarachnoid hemorrhage (SAH) has been recognized and suspected to contribute to cerebral ischemia. A recent study found that ultra-early cerebral micro-thrombosis occured four hours after experimental SAH. The number of thrombotic microvessels correlated with brain-blood barrier disruption and neuronal injury. If acute cerebral micro-thrombi also occur in humans, is it time to develop a therapy with systemic thrombolysis for SAH patients?

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