穆勒光学相干断层扫描检测小鼠皮肤癌的初步研究。

IF 2.3 3区医学 Q2 OPTICS

Journal of Innovative Optical Health Sciences Pub Date : 2009-07-01 DOI:10.1142/s1793545809000577

Miloš Todorović, Shuliang Jiao, George Stoica, Lihong V Wang

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引用次数: 3

摘要

我们报道了使用连续源偏振调制的基于光纤的穆勒矩阵光学相干断层扫描(OCT)系统对senar小鼠早期皮肤癌进行体内成像。在样品臂上耦合了一个自制的手持式光学扫描和光束传送光学探头。OCT图像显示癌前乳头状瘤形成导致的皮肤形态学变化与组织学一致，从而证明了该系统在早期皮肤癌检测中的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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PRELIMINARY STUDY ON SKIN CANCER DETECTION IN SENCAR MICE USING MUELLER OPTICAL COHERENCE TOMOGRAPHY.

We report on the use of a fiber-based Mueller-matrix optical coherence tomography (OCT) system with continuous source-polarization modulation for in vivo imaging of early stages of skin cancer in SENCAR mice. A homemade hand-held probe with integrated optical scanning and beam delivering optics was coupled in the sample arm. The OCT images show the morphological changes in skin resulting from pre-cancerous papilloma formations that are consistent with histology, thus demonstrating the system's potential for early skin cancer detection.

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来源期刊

Journal of Innovative Optical Health Sciences OPTICS-RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

CiteScore

4.50

自引率

20.00%

发文量

审稿时长

>12 weeks

期刊介绍： JIOHS serves as an international forum for the publication of the latest developments in all areas of photonics in biology and medicine. JIOHS will consider for publication original papers in all disciplines of photonics in biology and medicine, including but not limited to: -Photonic therapeutics and diagnostics- Optical clinical technologies and systems- Tissue optics- Laser-tissue interaction and tissue engineering- Biomedical spectroscopy- Advanced microscopy and imaging- Nanobiophotonics and optical molecular imaging- Multimodal and hybrid biomedical imaging- Micro/nanofabrication- Medical microsystems- Optical coherence tomography- Photodynamic therapy. JIOHS provides a vehicle to help professionals, graduates, engineers, academics and researchers working in the field of intelligent photonics in biology and medicine to disseminate information on the state-of-the-art technique.