尼安德特人和长毛象分子相似性:基因相似性可能是寒冷适应套件的基础。

4区 生物学 Q2 Medicine
Meidad Kislev, Ran Barkai
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引用次数: 1

摘要

随着近几十年来基于基因的研究的不断发展,在进化过程中检查结构中发生的变化变得越来越容易。在进化研究的前沿,一个有趣的主题是环境压力如何通过表观遗传适应影响物种进化。这篇文章介绍了两种灭绝的哺乳动物适应寒冷环境的可用分子成分:猛犸象和尼安德特人。这两个物种在中更新世和上更新世期间在欧洲相似的地理和环境环境中共存,它们都是非洲祖先的直系后代,尽管它们都在中更新世期间完全进化并适应了欧洲。作者通过回顾在两个基因组中发现的与寒冷气候适应相关的基因变异和等位基因的三个案例研究,评估了猛犸象和尼安德特人遗传成分之间的相似程度。他们的观察结果表明,这两个物种的冷适应特征在分子上可能存在相似之处。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neanderthal and Woolly Mammoth Molecular Resemblance: Genetic Similarities May Underlie Cold Adaptation Suite.

With the ongoing growth of gene-based research in recent decades, examining changes that have taken place in structures over the course of evolution has become increasingly accessible. One intriguing subject at the forefront of evolutionary research is how environmental pressures affect species evolution through epigenetic adaptation. This article presents the available molecular components of adaptation to cold environments in two extinct mammals: the woolly mammoth and the Neanderthal. These two species coexisted in similar geographic and environmental European settings during the Middle and Upper Pleistocene, and both were direct descendants of African ancestors, although both fully evolved and adapted in Europe during the Middle Pleistocene. The authors assessed the degree of resemblance between mammoth and Neanderthal genetic components by reviewing three case studies of relevant gene variants and alleles associated with cold-climate adaptation found in both genomes. Their observations present the likelihood of a molecular resemblance between the suites of cold adaptation traits in the two species.

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来源期刊
Human Biology
Human Biology 生物-生物学
CiteScore
1.90
自引率
0.00%
发文量
88
审稿时长
>12 weeks
期刊介绍: Human Biology publishes original scientific articles, brief communications, letters to the editor, and review articles on the general topic of biological anthropology. Our main focus is understanding human biological variation and human evolution through a broad range of approaches. We encourage investigators to submit any study on human biological diversity presented from an evolutionary or adaptive perspective. Priority will be given to interdisciplinary studies that seek to better explain the interaction between cultural processes and biological processes in our evolution. Methodological papers are also encouraged. Any computational approach intended to summarize cultural variation is encouraged. Studies that are essentially descriptive or concern only a limited geographic area are acceptable only when they have a wider relevance to understanding human biological variation. Manuscripts may cover any of the following disciplines, once the anthropological focus is apparent: human population genetics, evolutionary and genetic demography, quantitative genetics, evolutionary biology, ancient DNA studies, biological diversity interpreted in terms of adaptation (biometry, physical anthropology), and interdisciplinary research linking biological and cultural diversity (inferred from linguistic variability, ethnological diversity, archaeological evidence, etc.).
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