{"title":"热疗联合1%盐酸特比萘芬乳膏治疗一例移植后皮肤交替病。","authors":"Tomoka Harada, Takeshi Fukumoto, Korefumi Nakamura, Kenichiro Ohnuma, Chikako Nishigori","doi":"10.1111/ajd.13489","DOIUrl":null,"url":null,"abstract":"granules in the tissue (Fig. 1g). Based on this formation, the lesion was diagnosed as a haemorrhagic schwannoma with haemosiderin deposition. Typically, a schwannoma is globoid-shaped, is encapsulated, tan in colour and is homogeneously firm. Melanotic schwannoma, characterised by the accumulation of melanin, was a differential diagnosis in the present case. To help with diagnosis, Masson-Fontana staining and Perl staining are useful for determining whether the deposition is melanin or haemosiderin. Clinically, schwannomas are difficult to diagnose because they have considerable diversity in terms of clinical findings and behaviour. Recently, dermoscopy has become a useful tool for dermatologists to aid in the diagnose cutaneous tumours; however, there has been only one report describing the dermoscopic findings of schwannoma. Described are arborising vessels, structureless areas and brown pigmentation. On comparing the dermoscopic features with the histopathological findings the homogeneous brown areas corresponded to the leakage of red blood cells and haemosiderin deposition in the sub-epidermal portion of a fibrous capsule. The blue colour of the tumour could be caused by the Tyndall effect of haemosiderin pigment in the dermis. In summary, we reported a case of haemorrhagic schwannoma and its dermoscopic features. Our case and a previous report suggest that ‘homogeneous brown areas’ and ‘blue colour’ could be dermoscopic indicators of haemorrhagic schwannoma.","PeriodicalId":243138,"journal":{"name":"The Australasian journal of dermatology","volume":" ","pages":"e323-e325"},"PeriodicalIF":0.0000,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/ajd.13489","citationCount":"1","resultStr":"{\"title\":\"Successful thermotherapy combined with terbinafine hydrochloride 1% cream for cutaneous alternariosis in a post-transplantation patient.\",\"authors\":\"Tomoka Harada, Takeshi Fukumoto, Korefumi Nakamura, Kenichiro Ohnuma, Chikako Nishigori\",\"doi\":\"10.1111/ajd.13489\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"granules in the tissue (Fig. 1g). Based on this formation, the lesion was diagnosed as a haemorrhagic schwannoma with haemosiderin deposition. Typically, a schwannoma is globoid-shaped, is encapsulated, tan in colour and is homogeneously firm. Melanotic schwannoma, characterised by the accumulation of melanin, was a differential diagnosis in the present case. To help with diagnosis, Masson-Fontana staining and Perl staining are useful for determining whether the deposition is melanin or haemosiderin. Clinically, schwannomas are difficult to diagnose because they have considerable diversity in terms of clinical findings and behaviour. Recently, dermoscopy has become a useful tool for dermatologists to aid in the diagnose cutaneous tumours; however, there has been only one report describing the dermoscopic findings of schwannoma. Described are arborising vessels, structureless areas and brown pigmentation. On comparing the dermoscopic features with the histopathological findings the homogeneous brown areas corresponded to the leakage of red blood cells and haemosiderin deposition in the sub-epidermal portion of a fibrous capsule. The blue colour of the tumour could be caused by the Tyndall effect of haemosiderin pigment in the dermis. In summary, we reported a case of haemorrhagic schwannoma and its dermoscopic features. Our case and a previous report suggest that ‘homogeneous brown areas’ and ‘blue colour’ could be dermoscopic indicators of haemorrhagic schwannoma.\",\"PeriodicalId\":243138,\"journal\":{\"name\":\"The Australasian journal of dermatology\",\"volume\":\" \",\"pages\":\"e323-e325\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1111/ajd.13489\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Australasian journal of dermatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/ajd.13489\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2020/10/18 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Australasian journal of dermatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/ajd.13489","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2020/10/18 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
Successful thermotherapy combined with terbinafine hydrochloride 1% cream for cutaneous alternariosis in a post-transplantation patient.
granules in the tissue (Fig. 1g). Based on this formation, the lesion was diagnosed as a haemorrhagic schwannoma with haemosiderin deposition. Typically, a schwannoma is globoid-shaped, is encapsulated, tan in colour and is homogeneously firm. Melanotic schwannoma, characterised by the accumulation of melanin, was a differential diagnosis in the present case. To help with diagnosis, Masson-Fontana staining and Perl staining are useful for determining whether the deposition is melanin or haemosiderin. Clinically, schwannomas are difficult to diagnose because they have considerable diversity in terms of clinical findings and behaviour. Recently, dermoscopy has become a useful tool for dermatologists to aid in the diagnose cutaneous tumours; however, there has been only one report describing the dermoscopic findings of schwannoma. Described are arborising vessels, structureless areas and brown pigmentation. On comparing the dermoscopic features with the histopathological findings the homogeneous brown areas corresponded to the leakage of red blood cells and haemosiderin deposition in the sub-epidermal portion of a fibrous capsule. The blue colour of the tumour could be caused by the Tyndall effect of haemosiderin pigment in the dermis. In summary, we reported a case of haemorrhagic schwannoma and its dermoscopic features. Our case and a previous report suggest that ‘homogeneous brown areas’ and ‘blue colour’ could be dermoscopic indicators of haemorrhagic schwannoma.