1990-2017 年巴西因高体重指数造成的非传染性疾病负担:全球疾病负担研究的结果。

IF 3.2 2区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Mariana Santos Felisbino-Mendes, Ewerton Cousin, Deborah Carvalho Malta, Ísis Eloah Machado, Antonio Luiz Pinho Ribeiro, Bruce Bartholow Duncan, Maria Inês Schmidt, Diego Augusto Santos Silva, Scott Glenn, Ashkan Afshin, Gustavo Velasquez-Melendez
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引用次数: 0

摘要

背景:全世界肥胖症的发病率和疾病负担都在增加。在巴西,目前有一半以上的人口超重。然而,这一日益增长的风险因素对疾病负担的影响仍不确切。本研究利用 2017 年全球疾病负担(GBD)的结果,试图估算因高体重指数(BMI)导致的非传染性疾病造成的男女和各年龄段的死亡率和残疾调整生命年(DALYs)损失。这项研究还旨在描述巴西各州超重和肥胖的流行情况:方法:对 1990 年至 2017 年期间超重和肥胖的年龄标准化流行率进行了估算。采用比较风险评估来估算非传染性疾病的残疾调整寿命年数和死亡人数,以及与高体重指数相关的所有原因的残疾调整寿命年数和死亡人数:结果:在分析期间,超重和肥胖的流行率有所上升。总体而言,2017年巴西女性肥胖症的年龄标准化患病率(29.8%)高于男性(24.6%);然而,自1990年以来,男性肥胖症患病率的增幅(244.1%)高于女性(165.7%)。巴西北部和东北部地区各州的发病率负担增长幅度最大。总体而言,从 1990 年到 2017 年,高体重指数造成的负担也在增加。2017 年,高体重指数导致的死亡人数占总死亡人数的 12.3%(8.8-16.1%),占非传染性疾病造成的残疾调整寿命年损失总数的 8.4%(6.3-10.7%),分别高于 1990 年的 7.2%(4.1-10.8%)和 4.6%(2.4-6.0%)。风险暴露导致的变化是造成巴西体重指数负担增长的主要原因。2017 年,高体重指数导致 165 954 人死亡,5 095 125 人残疾调整寿命年数减少。事实证明,心血管疾病和糖尿病是最普遍的死亡原因,高体重指数造成的残疾调整寿命年数也是如此,与性别或州无关:这项研究表明,巴西各州按年龄标准化的肥胖症发病率不断上升。高体重指数在心血管疾病、糖尿病和各种死因的疾病负担中扮演着重要角色。评估暴露于高体重指数的水平和趋势以及由此造成的疾病负担,凸显了当前以肥胖症为重点的初级预防和公共卫生行动倡议的优先性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The burden of non-communicable diseases attributable to high BMI in Brazil, 1990-2017: findings from the Global Burden of Disease Study.

The burden of non-communicable diseases attributable to high BMI in Brazil, 1990-2017: findings from the Global Burden of Disease Study.

The burden of non-communicable diseases attributable to high BMI in Brazil, 1990-2017: findings from the Global Burden of Disease Study.

The burden of non-communicable diseases attributable to high BMI in Brazil, 1990-2017: findings from the Global Burden of Disease Study.

Background: The prevalence and burden of disease resulting from obesity have increased worldwide. In Brazil, more than half of the population is now overweight. However, the impact of this growing risk factor on disease burden remains inexact. Using the 2017 Global Burden of Disease (GBD) results, this study sought to estimate mortality and disability-adjusted life years (DALYs) lost to non-communicable diseases caused by high body mass index (BMI) in both sexes and across age categories. This study also aimed to describe the prevalence of overweight and obesity throughout the states of Brazil.

Methods: Age-standardized prevalence of overweight and obesity were estimated between 1990 and 2017. A comparative risk assessment was applied to estimate DALYs and deaths for non-communicable diseases and for all causes linked to high BMI.

Results: The prevalence of overweight and obesity increased during the period of analysis. Overall, age-standardized prevalence of obesity in Brazil was higher in females (29.8%) than in males (24.6%) in 2017; however, since 1990, males have presented greater rise in obesity (244.1%) than females (165.7%). Increases in prevalence burden were greatest in states from the North and Northeast regions of Brazil. Overall, burden due to high BMI also increased from 1990 to 2017. In 2017, high BMI was responsible for 12.3% (8.8-16.1%) of all deaths and 8.4% (6.3-10.7%) of total DALYs lost to non-communicable diseases, up from 7.2% (4.1-10.8%), and 4.6% (2.4-6.0%) in 1990, respectively. Change due to risk exposure is the leading contributor to the growth of BMI burden in Brazil. In 2017, high BMI was responsible for 165,954 deaths and 5,095,125 DALYs. Cardiovascular disease and diabetes have proven to be the most prevalent causes of deaths, along with DALYs caused by high BMI, regardless of sex or state.

Conclusions: This study demonstrates increasing age-standardized prevalence of obesity in all Brazilian states. High BMI plays an important role in disease burdens in terms of cardiovascular diseases, diabetes, and all causes of mortality. Assessing levels and trends in exposures to high BMI and the resulting disease burden highlights the current priority for primary prevention and public health action initiatives focused on obesity.

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来源期刊
Population Health Metrics
Population Health Metrics PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
6.50
自引率
0.00%
发文量
21
审稿时长
29 weeks
期刊介绍: Population Health Metrics aims to advance the science of population health assessment, and welcomes papers relating to concepts, methods, ethics, applications, and summary measures of population health. The journal provides a unique platform for population health researchers to share their findings with the global community. We seek research that addresses the communication of population health measures and policy implications to stakeholders; this includes papers related to burden estimation and risk assessment, and research addressing population health across the full range of development. Population Health Metrics covers a broad range of topics encompassing health state measurement and valuation, summary measures of population health, descriptive epidemiology at the population level, burden of disease and injury analysis, disease and risk factor modeling for populations, and comparative assessment of risks to health at the population level. The journal is also interested in how to use and communicate indicators of population health to reduce disease burden, and the approaches for translating from indicators of population health to health-advancing actions. As a cross-cutting topic of importance, we are particularly interested in inequalities in population health and their measurement.
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