埃塞俄比亚西南部吉玛大学医学中心诊断为传染病的儿科患者用药错误及其影响因素:前瞻性观察研究

IF 2.1 Q3 PHARMACOLOGY & PHARMACY
Integrated Pharmacy Research and Practice Pub Date : 2020-09-15 eCollection Date: 2020-01-01 DOI:10.2147/IPRP.S264941
Desalegn Feyissa, Bezie Kebede, Ameha Zewudie, Yitagesu Mamo
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引用次数: 7

摘要

背景:儿科患者的用药错误被严重低估。儿科病人很容易受到用药错误的影响。幼儿和婴儿用药错误造成的潜在伤害更高。它导致严重的发病率和死亡率。因此,本研究旨在评估吉马大学医学中心诊断为感染性疾病的儿科患者用药错误及其影响因素。方法:对2018年4月1日至6月30日住院的儿科感染性疾病患者进行前瞻性观察研究。在解释研究目的后获得患者的书面知情同意。数据采用结构化问卷法收集。数据输入EpiData 4.0.2版本,导出到SPSS 21.0版本进行分析。为了确定用药错误的预测因素,我们进行了逆向逻辑回归分析。结果:在325名研究参与者中,136名(41.8%)患者在住院期间至少有一次用药错误。136例患者共发现273例用药错误。用药错误多发于处方94期(34.4%)。最常见的用药差错类型是错误剂量72例(26.4%)和错误频次47例(17.2%)。存在疾病合并症(AOR=1.64, 95%CI=1.01-2.67)、男性(AOR=1.79, 95%CI:1.13-2.86)、存在两种传染病(AOR=1.96, 95%CI: 1.20-3.23)和三种以上传染病(AOR=2.04, 95%CI: 1.03-4.01)是用药错误发生的独立预测因素。结论与建议:研究区儿科感染性疾病患者用药错误较为常见。合并症的存在、男性和传染病的数量与用药错误的发生有关。因此,为了减少研究环境中的用药错误,需要电子处方、计算机化提供者订单输入、药物调节以及临床药师与其他卫生专业人员的合作。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Medication Error and Its Contributing Factors Among Pediatric Patients Diagnosed with Infectious Diseases Admitted to Jimma University Medical Center, Southwest Ethiopia: Prospective Observational Study.

Medication Error and Its Contributing Factors Among Pediatric Patients Diagnosed with Infectious Diseases Admitted to Jimma University Medical Center, Southwest Ethiopia: Prospective Observational Study.

Background: Medication errors in pediatric patients are grossly underreported. Pediatric patients are quite susceptible to medication errors. Potential injury by medication error is higher in young children and infants. It results in serious morbidity and mortality. Thus, this study aimed to assess medication error and its contributing factors among pediatric patients diagnosed with infectious diseases admitted to Jimma University Medical Center.

Methods: A prospective observational study was conducted among pediatric patients with infectious diseases admitted from April 1 to June 30, 2018. The patient's written informed consent was obtained after explaining the purpose of the study. The data were collected by structured questionnaire. Data were entered into EpiData version 4.0.2 and then exported to SPSS version 21.0 for analysis. To identify the predictors of medication error, backward logistic regression analysis was done.

Results: From a total of the 325 study participants, 136 (41.8%) patients had at least one medication error during their hospital stay. A total of 273 medication errors were identified among 136 patients. Medication errors frequently occurred at prescribing stage 94 (34.4%). The most common types of medication errors were wrong dosing 72 (26.4%) and wrong frequency 47 (17.2%). Presence of disease comorbidity (AOR=1.64, 95%CI=1.01-2.67), being male (AOR=1.79, 95%CI:1.13-2.86) and presence of two infectious diseases (AOR=1.96, 95%CI: 1.20-3.23) and more than three infectious diseases (AOR=2.04, 95%CI: 1.03-4.01) were independent predictors of medication error occurrence.

Conclusion and recommendation: Medication errors were common in pediatric patients with infectious diseases in the study area. Presence of comorbidities, being male and the number of infectious diseases were associated with the occurrence of medication errors. Therefore, to reduce medication errors in the study setting, e-prescribing, computerized provider order entry, medication reconciliation, and collaboration of clinical pharmacists with other health professionals are needed.

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