P Igboeli, W Walker, A McHugh, A Sultan, A Al-Hendy
{"title":"子宫肌瘤的负担:非洲视角:行动呼吁和干预机会》。","authors":"P Igboeli, W Walker, A McHugh, A Sultan, A Al-Hendy","doi":"10.18314/cogo.v2i1.1701","DOIUrl":null,"url":null,"abstract":"<p><p>Black women carry the burden of uterine fibroids, (AKA uterine leiomyomas), at a much higher rate than their racial counterparts. Thus, increasing awareness and discovering a solution to an endemic problem that plagues Sub-Saharan Africa is of critical importance, not only for the region itself, but also for the medical community globally. A collaborative, patient oriented, cost effective, and culturally sensitive approach must be at the forefront of this endeavor. While the exact pathogenesis of uterine fibroid development remains elusive, the racial disparity is well documented. Moreover, in the developed world, women are able to seek treatment through surgical and non-surgical means; however, sub-Saharan regions face their own challenges that, if not addressed, can ultimately extinguish the lives of many suffering women. Unfortunately, the literature is scarce on how to prevent fibroid development, which may be critical for women who do not have access to effective interventions. Recent research from our group and others has shown that vitamin D deficiency plays an important role in fibroid development and may be a preventable risk factor. Daily vitamin D supplementation is a low cost, effective intervention that could be implemented throughout the Sub-Saharan region. Similarly, education and increased awareness as to the nature and symptoms of uterine fibroids could improve the quality of life, remove negative social stigma, and reduce morbidity and mortality rates in women who seek medical care with advanced uterine fibroids.</p>","PeriodicalId":92345,"journal":{"name":"Current opinion in gynecology and obstetrics","volume":"2 1","pages":"287-294"},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344264/pdf/","citationCount":"0","resultStr":"{\"title\":\"Burden of Uterine Fibroids: An African Perspective, A Call for Action and Opportunity for Intervention.\",\"authors\":\"P Igboeli, W Walker, A McHugh, A Sultan, A Al-Hendy\",\"doi\":\"10.18314/cogo.v2i1.1701\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Black women carry the burden of uterine fibroids, (AKA uterine leiomyomas), at a much higher rate than their racial counterparts. Thus, increasing awareness and discovering a solution to an endemic problem that plagues Sub-Saharan Africa is of critical importance, not only for the region itself, but also for the medical community globally. A collaborative, patient oriented, cost effective, and culturally sensitive approach must be at the forefront of this endeavor. While the exact pathogenesis of uterine fibroid development remains elusive, the racial disparity is well documented. Moreover, in the developed world, women are able to seek treatment through surgical and non-surgical means; however, sub-Saharan regions face their own challenges that, if not addressed, can ultimately extinguish the lives of many suffering women. Unfortunately, the literature is scarce on how to prevent fibroid development, which may be critical for women who do not have access to effective interventions. Recent research from our group and others has shown that vitamin D deficiency plays an important role in fibroid development and may be a preventable risk factor. Daily vitamin D supplementation is a low cost, effective intervention that could be implemented throughout the Sub-Saharan region. Similarly, education and increased awareness as to the nature and symptoms of uterine fibroids could improve the quality of life, remove negative social stigma, and reduce morbidity and mortality rates in women who seek medical care with advanced uterine fibroids.</p>\",\"PeriodicalId\":92345,\"journal\":{\"name\":\"Current opinion in gynecology and obstetrics\",\"volume\":\"2 1\",\"pages\":\"287-294\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7344264/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current opinion in gynecology and obstetrics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18314/cogo.v2i1.1701\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2019/8/11 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current opinion in gynecology and obstetrics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18314/cogo.v2i1.1701","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2019/8/11 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
黑人妇女罹患子宫肌瘤(又名子宫纵隔肌瘤)的比例远远高于其他种族的妇女。因此,提高人们对这一困扰撒哈拉以南非洲地区的地方性问题的认识并找到解决办法,不仅对该地区本身,而且对全球医学界都至关重要。在这一努力中,必须首先采取合作、以患者为导向、具有成本效益和文化敏感性的方法。虽然子宫肌瘤的确切发病机理仍然难以捉摸,但种族差异却有据可查。此外,在发达国家,妇女可以通过手术和非手术手段寻求治疗;然而,撒哈拉以南地区却面临着自身的挑战,如果不加以解决,最终可能会夺去许多受苦妇女的生命。遗憾的是,关于如何预防子宫肌瘤发展的文献很少,而这对于无法获得有效干预的妇女来说可能至关重要。我们小组和其他小组最近的研究表明,维生素 D 缺乏在子宫肌瘤的发展中起着重要作用,而且可能是一个可预防的风险因素。每日补充维生素 D 是一种低成本、有效的干预措施,可以在整个撒哈拉以南地区实施。同样,对子宫肌瘤的性质和症状进行教育并提高人们的认识,可以改善晚期子宫肌瘤妇女的生活质量,消除负面的社会耻辱感,降低其发病率和死亡率。
Burden of Uterine Fibroids: An African Perspective, A Call for Action and Opportunity for Intervention.
Black women carry the burden of uterine fibroids, (AKA uterine leiomyomas), at a much higher rate than their racial counterparts. Thus, increasing awareness and discovering a solution to an endemic problem that plagues Sub-Saharan Africa is of critical importance, not only for the region itself, but also for the medical community globally. A collaborative, patient oriented, cost effective, and culturally sensitive approach must be at the forefront of this endeavor. While the exact pathogenesis of uterine fibroid development remains elusive, the racial disparity is well documented. Moreover, in the developed world, women are able to seek treatment through surgical and non-surgical means; however, sub-Saharan regions face their own challenges that, if not addressed, can ultimately extinguish the lives of many suffering women. Unfortunately, the literature is scarce on how to prevent fibroid development, which may be critical for women who do not have access to effective interventions. Recent research from our group and others has shown that vitamin D deficiency plays an important role in fibroid development and may be a preventable risk factor. Daily vitamin D supplementation is a low cost, effective intervention that could be implemented throughout the Sub-Saharan region. Similarly, education and increased awareness as to the nature and symptoms of uterine fibroids could improve the quality of life, remove negative social stigma, and reduce morbidity and mortality rates in women who seek medical care with advanced uterine fibroids.