癌症生育能力保存:来自巴西社会项目的报告。

IF 1.9
Caroline Z Berton, Caroline Brogliato, Ivan H Yoshida, Laura T Vellez, Claudia H Suganuma, Emerson B Cordts, Gabriel S Conceição, Caio P Barbosa
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引用次数: 3

摘要

目的:介绍巴西癌症生育能力保存社会项目的临床和实验室数据。方法:我们于2011年7月至2018年12月进行了描述性观察研究。在开始肿瘤治疗前,246名患者从巴西圣安德罗一家私人辅助生殖诊所的社会项目中纳入卵母细胞冷冻保存。结果:246例癌症患者在开始癌症治疗前采取了保留生育能力的措施。这些人被诊断出患有27种不同类型的癌症,其中乳腺癌最为普遍。2528个MII卵母细胞(平均10.3个/例)被玻璃化。4名患者解冻卵母细胞进行体外受精,3名患者进行胚胎移植,1名患者成功怀孕。结论:保留生育能力为患者,特别是育龄患者提供了一种可行的方法,可以在不影响未来妊娠的情况下进行癌症治疗。重要的是,专业人员应适当地向肿瘤患者提供咨询,这样,如果他们愿意,他们就有可能保证保留她的生育能力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cancer fertility preservation: a report from a Brazilian social program.

Objective: To present clinical and laboratory data of a Brazilian social program for cancer fertility preservation.

Methods: We carried out a descriptive observational study between July 2011 and December 2018. 246 patients were included from a social program in a private assisted reproduction clinic in Santo André/Brazil for oocyte cryopreservation before starting oncological treatment.

Results: 246 cancer patients resorted to fertility preservation before initiating cancer treatment. These were diagnosed with 27 different types of cancer, and the breast type is the most prevalent. 2528 MII oocytes (mean of 10.3 oocytes per patient) were vitrified. Four patients thawed their oocytes to submit in vitro fertilization, three had embryos transferred and one achieved pregnancy.

Conclusion: Preservation of fertility offers patients, especially at reproductive age, a viable way to perform their cancer treatment without compromising future gestation. It is important that professionals duly counsel oncological patients so, if they wish, they can have the possibility to guarantee her fertility preserved.

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