一例腹膜透析患者无症状透析液混浊和导管内重复凝块。

Biomedicine Hub Pub Date : 2019-07-08 eCollection Date: 2019-05-01 DOI:10.1159/000500944
Tian Xu, Jingyuan Xie, Weiming Wang, Hong Ren, Nan Chen
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引用次数: 2

摘要

1例女性患者接受腹膜透析2.5年。患者发现腹膜透析流出液持续浑浊3个月,无腹痛。腹膜流出液样本的重复常规检查显示白细胞计数升高和嗜酸性粒细胞数量增加。此外,在Tenckhoff导管内发现一个小黑点。腹膜液培养未见细菌和真菌。考虑特发性嗜酸性腹膜炎,给予口服皮质类固醇治疗。不久之后,透析流出物变得清澈。然而,嗜酸性腹膜炎在暂停皮质类固醇治疗后立即复发。更糟糕的是,导管功能障碍发生,可能是由于血栓逐渐形成的斑点。最后取出导管,进行病理检查。结果表明,血凝块由真菌孢子、菌丝和嗜酸性粒细胞组成。这个病例提醒我们,当血栓形成时应怀疑真菌性腹膜炎。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Asymptomatic Dialysate Turbidity and Repeated Intraductal Clots in a Peritoneal Dialysis Patient.

Asymptomatic Dialysate Turbidity and Repeated Intraductal Clots in a Peritoneal Dialysis Patient.

Asymptomatic Dialysate Turbidity and Repeated Intraductal Clots in a Peritoneal Dialysis Patient.

Asymptomatic Dialysate Turbidity and Repeated Intraductal Clots in a Peritoneal Dialysis Patient.

A female patient underwent peritoneal dialysis for 2.5 years. She was found to have a constant turbid peritoneal dialysis effluent for 3 months without abdominal pain. Repeated routine tests of peritoneal effluent samples showed an elevated white blood cell count and an increased number of eosinophils. Additionally, a small black spot was found inside the Tenckhoff catheter. The presence of bacteria and fungi was negative by peritoneal fluid culture. Idiopathic eosinophilic peritonitis was considered, and oral corticosteroid treatment was administered. Soon after, the dialysis effluent became clear. However, eosinophilic peritonitis immediately relapsed after the corticosteroid therapy was suspended. Even worse, catheter dysfunction occurred, likely due to a clot that gradually formed from the spot. Finally, the catheter was removed, and a pathological examination was performed. It was revealed that the clot was composed of fungal spores and hyphae as well as eosinophils. This case reminds us that fungal peritonitis should be suspected when a clot forms.

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