物质诱发精神病的诊断稳定性

IF 5.2 3区 医学 Q1 PSYCHIATRY
Lucía Inchausti , Iñigo Gorostiza , Miguel Angel Gonzalez Torres , Rodrigo Oraa
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引用次数: 5

摘要

物质诱发性精神病(SIP)是一种精神病的名称,它开始于药物滥用的背景下,但在没有药物使用的情况下持续数天或数周。目前对这种精神疾病的纵向病程知之甚少,这表明有相当多的人继续被诊断为严重精神障碍(SMD)。本研究的目的是分析在我们的环境中SIP到SMD的进展,以及可能参与这种转换的可能因素。材料和方法我们采用回顾性队列随访设计。我们对2002年1月至2015年12月Basurto大学医院精神科出院患者的所有诊断进行了综合分析。除了社会人口和临床数据外,还收集了大麻素、类阿片、安非他明、可卡因和酒精消费的信息。采用描述性分析、Kaplan-Meier生存曲线和Cox回归分析资料。结果116例患者中,78.4%为男性,平均年龄33.0岁(SD: 8.9)岁,44.0%为单身;31.0%有精神科家族史;最常使用的物质是大麻(60.3%),其次是可卡因(40.5%)。16年内诊断转化为SMD的累积风险为41.6% (95% CI: 32.2-52.2),平均36.43个月。结论:在SIP发作的干预措施中,我们必须记住,很大一部分将在前三年进展为SMD。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Estabilidad diagnóstica en la psicosis inducida por sustancias

Introduction

Substance-induced psychosis (SIP) is the name given to a psychosis that starts in the context of substance abuse but persists for days and weeks with no substance use. There is as yet little knowledge about the longitudinal course of this psychosis, which suggests that significant numbers go on to be diagnosed with a severe mental disorder (SMD). The objective of this study was to analyse the progression of SIP to SMD in our environment and the possible factors that may be involved in that conversion.

Material and methods

We used a retrospective cohort follow-up design. We reviewed all diagnoses of patients discharged from the psychiatric hospitalisation unit of the University Hospital of Basurto from January 2002 to December 2015 inclusively. In addition to sociodemographic and clinical data, information was collected on the consumption of cannabinoids, opioids, amphetamines, cocaine and alcohol. The data were analysed using descriptive analysis, Kaplan-Meier survival curves and Cox regression.

Results

Of the 116 patients, 78.4% were male, had an average age of 33.0 (SD: 8.9) years and 44.0% were single; 31.0% had a psychiatric family history; the most commonly used substance was cannabis (60.3%), followed by cocaine (40.5%). The cumulative risk of diagnostic conversion to an SMD in 16 years was 41.6% (95% CI: 32.2-52.2) over a mean 36.43 months.

Conclusions

In interventions in episodes of SIP we must bear in mind that a significant proportion will progress to an SMD in the first three years.

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来源期刊
自引率
3.30%
发文量
58
期刊介绍: The Spanish Journal of Psychiatry and Mental Health (SJPMH), incorporated into ISSN 1888-9891, is the official scientific publication of the Spanish Society of Psychiatry and Mental Health. The journal focuses on studying mental illnesses, their pathological processes, and their psychosocial consequences, and aims to disseminate scientific advances in all areas related to mental health and illness. SJPMH accepts unpublished works on psychiatry and mental health, including their medical and social implications. The journal provides space for research in the biological, clinical, and psychosocial fields. Manuscripts undergo peer-review by external reviewers before being accepted for publication. SJPMH is indexed in Index Medicus/Medline, IBECS, Social Sciences Citation Index Journal Citation Reports/Social Sciences Edition, and Current Contents/Social and Behavioral Sciences.
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