David M Murray, Monica Taljaard, Elizabeth L Turner, Stephanie M George
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Essential Ingredients and Innovations in the Design and Analysis of Group-Randomized Trials.
This article reviews the essential ingredients and innovations in the design and analysis of group-randomized trials. The methods literature for these trials has grown steadily since they were introduced to the biomedical research community in the late 1970s, and we summarize those developments. We review, in addition to the group-randomized trial, methods for two closely related designs, the individually randomized group treatment trial and the stepped-wedge group-randomized trial. After describing the essential ingredients for these designs, we review the most important developments in the evolution of their methods using a new bibliometric tool developed at the National Institutes of Health. We then discuss the questions to be considered when selecting from among these designs or selecting the traditional randomized controlled trial. We close with a review of current methods for the analysis of data from these designs, a case study to illustrate each design, and a brief summary.
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The Annual Review of Public Health has been a trusted publication in the field since its inception in 1980. It provides comprehensive coverage of important advancements in various areas of public health, such as epidemiology, biostatistics, environmental health, occupational health, social environment and behavior, health services, as well as public health practice and policy.
In an effort to make the valuable research and information more accessible, the current volume has undergone a transformation. Previously, access to the articles was restricted, but now they are available to everyone through the Annual Reviews' Subscribe to Open program. This open access approach ensures that the knowledge and insights shared in these articles can reach a wider audience. Additionally, all the published articles are licensed under a CC BY license, allowing users to freely use, distribute, and build upon the content, while giving appropriate credit to the original authors.
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