自体脂肪移植在乳房切除术和保乳手术后重建中的应用:一项更新的系统评价方案

IF 1.1 Q3 SURGERY
Riaz A. Agha , Mimi R. Borrelli , Naeem Dowlut , Mohsin F. Butt , Sam Freeman , Ter-Er Orkar , Dennis P. Orgill
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引用次数: 1

摘要

自体脂肪移植(AFG)在乳房再造手术中的应用越来越被人们所接受,但对其有效性和安全性的担忧仍然存在。我们提出了一个系统评价的方案,旨在更新我们之前对AFG的一些结果的系统评价的发现。方法系统评价已先验注册(注册号:reviewregistry308)。所有研究设计,包括随机对照试验、队列研究、病例对照研究和病例报告/系列,报告原始数据,包括在乳房切除术或保乳手术后接受AFG进行乳房重建的妇女。将评估六个分类结果:肿瘤学;临床;审美/功能;patient-reported;过程;和辐射。搜索策略将用于调查“脂肪移植和乳房重建”。2014年4月1日至2017年8月21日期间将检索电子数据库:PubMed、MEDLINE®、EMBASE、SCOPUS、CINAHL、PsychINFO、SciELO、Cochrane图书馆,包括Cochrane对照试验中央注册库(Central)、效果评价摘要数据库(DARE)、Cochrane方法学注册库、卫生技术评估数据库、NHS经济评估数据库和Cochrane群组、ClinicalTrials.gov、当前对照试验数据库、世界卫生组织(WHO)国际临床试验注册平台、UpToDate.com、NHS证据和约克中心的审查和传播。灰色文献将被搜索。两个训练有素的独立团队将筛选所有标题和摘要以及相关全文,以确定是否符合资格。数据将在标准化提取字段下提取到预格式化的数据库中。该系统综述将发表在同行评议的期刊上,并在整形、重建和美容外科以及外科肿瘤学领域的国内和国际会议上发表。这项工作将以电子方式和印刷品传播。本署会以电邮或直接沟通的方式,向有关人士分发有关检讨结果的简短报告。该审查旨在指导医疗保健实践和政策。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Use of autologous fat grafting in reconstruction following mastectomy and breast conserving surgery: An updated systematic review protocol

Use of autologous fat grafting in reconstruction following mastectomy and breast conserving surgery: An updated systematic review protocol

Introduction

Use of autologous fat grafting (AFG) for breast reconstructive surgery is gaining acceptance, but concerns regarding its efficacy and safety remain. We present a protocol for a systematic review that aims to update the findings since our previous systematic review on a number of outcomes of AFG.

Methods

The systematic review has been registered a priori (UIN: reviewregistry308). All study designs, including randomised controlled trials, cohort studies, case-controlled studies and case reports/series, reporting original data, on women undergoing AFG for breast reconstruction following mastectomy or breast conserving surgery, will be included. Six categorical outcomes will be assessed: oncological; clinical; aesthetic/functional; patient-reported; process; and radiological.

The search strategy will be devised to investigate ‘fat grafting and breast reconstruction’. Electronic databases will be searched, 01 April 2014 to 21 August 2017: PubMed, MEDLINE®, EMBASE, SCOPUS, CINAHL, PsychINFO, SciELO, The Cochrane Library, including the Cochrane Central Register of Controlled Trials (CENTRAL), Database of Abstracts of Reviews of Effect (DARE), the Cochrane Methodology Register, Health Technology Assessment Database, the NHS Economic Evaluation Databases and Cochrane Groups, ClinicalTrials.gov, Current Controlled Trials Database, the World Health Organisation (WHO) International Clinical Trials Registry Platform, UpToDate.com, NHS Evidence and the York Centre for Reviews and Dissemination. Grey literature will be searched. Two trained, independent teams will screen all titles and abstracts, and relevant full texts, for eligibility. Data will be extracted under standardised extraction fields into a preformatted database.

Ethics and dissemination

The systematic review will be published in a peer-reviewed journal and presented at national and international meetings within fields of plastic, reconstructive and aesthetic surgery, and surgical oncology. The work will be disseminated electronically and in print. Brief reports of the review and findings will be disseminated to interested parties through email and direct communication. The review aims to guide healthcare practice and policy.

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来源期刊
自引率
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发文量
12
期刊介绍: IJS Protocols is the first peer-reviewed, international, open access journal seeking to publish research protocols across across the full breadth of the surgical field. We are aim to provide rapid submission to decision times whilst maintaining a high quality peer-review process.
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