丹麦一组遗传性出血性毛细血管扩张患者记录的鼻塞疗效。

IF 1.9 3区医学 Q2 OTORHINOLARYNGOLOGY

European Archives of Oto-Rhino-Laryngology Pub Date : 2020-03-01 Epub Date: 2019-12-16 DOI:10.1007/s00405-019-05758-1

Jonas Hjelm Andersen, Anette Drøhse Kjeldsen

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引用次数: 5

摘要

背景:鼻腔封闭术，也被称为改良杨氏手术，于2008年在丹麦被引入，作为遗传性出血性毛细血管扩张(HHT)患者严重鼻出血的手术解决方案。本研究的目的是从患者的角度报告手术的总体满意度以及并发症的发生。方法:纳入2008年至2018年所有行鼻闭合术的HHT患者。使用格拉斯哥获益量表(GBI)评估患者的术后并发症和主观结果。结果:10例患者纳入研究，平均观察时间64个月。没有一个患者完全没有并发症，并且在一个病例中要求逆转。血红蛋白水平平均上升了2.8 g/dl。术后GBI平均评分为38.05分。十分之九的患者会向其他HHT患者推荐鼻塞。结论:患者强烈推荐鼻塞术，但由于术后并发症的发生率，该手术应保留给精心挑选的HHT患者。

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Patient-recorded benefit from nasal closure in a Danish cohort of patients with hereditary haemorrhagic telangiectasia.

Background: Nasal closure, also known as the modified Young's procedure was introduced in Denmark in 2008, as a surgical solution to severe epistaxis in patients with hereditary haemorrhagic telangiectasia (HHT). The objective of this study was to report the overall satisfaction of the procedure from a patient's point of view as well as the occurrence of complications.

Methods: All the HHT patients who underwent nasal closure from 2008 to 2018 were included in the study. The patients were evaluated for postoperative complications and subjective outcome using Glasgow Benefit Inventory (GBI).

Results: Ten patients were included in the study and were observed for a mean of 64 months. None of the patients was completely free of complications, and reversal was requested in a single case. Haemoglobin levels rose with an average of 2.8 g/dl. The average GBI score after surgery was 38.05. Nine of ten patients would recommend nasal closure to fellow HHT patients.

Conclusion: Nasal closure is highly recommended among patients, but due to the rate of postoperative complications, the procedure should be reserved for a carefully selected group of HHT patients.

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来源期刊

European Archives of Oto-Rhino-Laryngology 医学-耳鼻喉科学

CiteScore

5.30

自引率

7.70%

发文量

537

审稿时长

2-4 weeks

期刊介绍： Official Journal of European Union of Medical Specialists – ORL Section and Board Official Journal of Confederation of European Oto-Rhino-Laryngology Head and Neck Surgery "European Archives of Oto-Rhino-Laryngology" publishes original clinical reports and clinically relevant experimental studies, as well as short communications presenting new results of special interest. With peer review by a respected international editorial board and prompt English-language publication, the journal provides rapid dissemination of information by authors from around the world. This particular feature makes it the journal of choice for readers who want to be informed about the continuing state of the art concerning basic sciences and the diagnosis and management of diseases of the head and neck on an international level. European Archives of Oto-Rhino-Laryngology was founded in 1864 as "Archiv für Ohrenheilkunde" by A. von Tröltsch, A. Politzer and H. Schwartze.