饮食质量与肥胖相关代谢风险之间的关系。

Q3 Medicine

Human Antibodies Pub Date : 2020-01-01 DOI:10.3233/HAB-190387

Ahmed Abdulahi Abdurahman, Mohammed Bule, Leyla Azadbakhat, Masoume Fallahyekta, Ali Parouhan, Mostefa Qorbani, Ahmad Reza Dorosty

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引用次数: 4

摘要

背景:本研究的目的是在伊朗肥胖成年人的代表性样本中，研究通过饮食的炎症潜力和替代健康饮食指数-2010 (AHEI-2010)测量的饮食质量与肥胖相关代谢风险之间的关系。方法:对300名肥胖成人进行横断面研究。采用经验证的168项半定量食物频率问卷(FFQ)评估膳食摄入量。采用AHEI-2010和经验饮食炎症模式(EDIP)评分来测量饮食质量。结果:与低四分位数的参与者相比，AHEI-2010中高四分位数的参与者血清甘油三酯(TG)水平较低，体重指数(BMI)较高。EDIP评分越高的患者血清TG水平越高。在控制了潜在的共变量后，与第一个四分位数(Q4 vs Q1: OR, 0.3 (95% CI: 0.1-0.8)， p趋势= 0.02)的患者相比，较高的空腹血糖(FBG)发生率降低70% [Q4 vs Q1: OR, 0.3 (95% CI: 1.1-5.5)， p趋势= 0.05]。EDIP评分最高四分位数的患者与最低四分位数(Q4 vs Q1: OR, 2.4 (95% CI: 1.1-5.5)， p趋势= 0.05]的患者相比，高舒张压的发生率高出60%。结论:高质量的饮食结合更多的抗炎饮食可能对降低肥胖相关的代谢风险有潜在的好处。

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The association between diet quality and obesity-related metabolic risks.

Background: The aim of this study was to examine the association between dietary quality measured by inflammatory potential of a diet and Alternative Healthy Eating Index-2010 (AHEI-2010), and obesity-related metabolic risks in a representative sample of Iranian obese adults.

Method: This cross-sectional study was conducted on 300 obese adults. Dietary intake was assessed using a validated 168-item semi-quantitative food frequency questionnaire (FFQ). Diet quality was measured using AHEI-2010 and Empirical Dietary Inflammatory Pattern (EDIP) scores.

Results: Those in the upper quartile of AHEI-2010 were associated with lower serum level of triglycerides (TG), and higher body mass index (BMI), compared to participants in the lower quartile. Those in the higher quartile of EDIP score were associated with higher serum level of TG. Greater adherence to AHEI-2010 had 70% lower odds of high fasting blood glucose (FBG), compared with those in the first quartile [Q4 vs Q1: OR, 0.3 (95% CI: 0.1-0.8), p trend = 0.02] Those in the highest quartile of EDIP score had a 60% higher odds of high diastolic blood pressure, compared with those in the lowest quartile [Q4 vs Q1: OR, 2.4 (95% CI: 1.1-5.5), p trend = 0.05] after controlling for potential covariates.

Conclusions: High diet quality incorporating more anti-inflammatory diet may have a potential benefit in reducing obesity-related metabolic risks.

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来源期刊

Human Antibodies Medicine-Immunology and Allergy

CiteScore

3.50

自引率

0.00%

发文量

期刊介绍： Human Antibodies is an international journal designed to bring together all aspects of human hybridomas and antibody technology under a single, cohesive theme. This includes fundamental research, applied science and clinical applications. Emphasis in the published articles is on antisera, monoclonal antibodies, fusion partners, EBV transformation, transfections, in vitro immunization, defined antigens, tissue reactivity, scale-up production, chimeric antibodies, autoimmunity, natural antibodies/immune response, anti-idiotypes, and hybridomas secreting interesting growth factors. Immunoregulatory molecules, including T cell hybridomas, will also be featured.