{"title":"基于袖带的中央血流动力学振荡测量:影响日本正常血压个体中央升高压的因素。","authors":"Masakazu Obayashi, Shigeki Kobayashi, Michiaki Kohno, Tomoko Nakashima, Masafumi Yano","doi":"10.1159/000496151","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Recently, new devices using oscillometric cuff have been developed to derive central blood pressure (BP) waveform from brachial BP waveform. Late systolic pressure augmentation of central BP waveform is a marker of central hemodynamics. Mobil-O-Graph, a cuff-based oscillometric device, can assess central augmentation pressure (AP) together with central BP. Central AP measurement using the Mobil-O-Graph in the European population was reported to be associated with age and sex. However, factors influencing central AP in the Asian population have not been shown.</p><p><strong>Objectives and methods: </strong>We enrolled 110 normotensive volunteers (50 men; age range, 21‒76 years). Central BP and AP were measured using the Mobil-O-Graph on the left arm with the subjects in the seated position after resting for at least 5 min. We compared central hemodynamics between the sexes. We investigated factors influencing central AP in uni- and multivariate linear regression analyses and age-related change in central AP using the Mobil-O-Graph in healthy Japanese individuals.</p><p><strong>Results: </strong>Central AP were lower in men than in women (5.5 ± 2.8 vs. 11.0 ± 4.7 mm Hg, <i>p</i> < 0.001). The central AP in the total cohort was positively correlated with age (<i>r</i> = 0.325, <i>p</i> < 0.001) and inversely correlated with height (<i>r</i> = -0.601, <i>p</i> < 0.001) in the Pearson correlations. In multivariate regression analysis, the parameters influencing central AP (<i>R</i>>sup<2>/sup< = 0.467) were age (β = 0.097, <i>p</i> < 0.001), sex (β = -2.890, <i>p</i> = 0.010), and height (β = -0.153, <i>p</i> = 0.031). The central AP (10.0 ± 4.8 mm Hg) in the ≥50-year-old group significantly increased compared with those in the 20- to 39-year-old group (6.7 ± 4.2 mm Hg, <i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>Age, sex, and height influenced central AP, as assessed using the Mobil-O-Graph. Age-related increase in central AP was observed in normotensive Japanese individuals. Brachial cuff-based waveform recordings using the Mobil-O-Graph are feasible for the estimation of central AP in the Asian population.</p>","PeriodicalId":29774,"journal":{"name":"Pulse","volume":"6 3-4","pages":"161-168"},"PeriodicalIF":7.3000,"publicationDate":"2019-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000496151","citationCount":"2","resultStr":"{\"title\":\"Cuff-Based Oscillometric Measurements of Central Hemodynamics: Factors Influencing Central Augmentation Pressure in Normotensive Japanese Individuals.\",\"authors\":\"Masakazu Obayashi, Shigeki Kobayashi, Michiaki Kohno, Tomoko Nakashima, Masafumi Yano\",\"doi\":\"10.1159/000496151\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Recently, new devices using oscillometric cuff have been developed to derive central blood pressure (BP) waveform from brachial BP waveform. Late systolic pressure augmentation of central BP waveform is a marker of central hemodynamics. Mobil-O-Graph, a cuff-based oscillometric device, can assess central augmentation pressure (AP) together with central BP. Central AP measurement using the Mobil-O-Graph in the European population was reported to be associated with age and sex. However, factors influencing central AP in the Asian population have not been shown.</p><p><strong>Objectives and methods: </strong>We enrolled 110 normotensive volunteers (50 men; age range, 21‒76 years). Central BP and AP were measured using the Mobil-O-Graph on the left arm with the subjects in the seated position after resting for at least 5 min. We compared central hemodynamics between the sexes. We investigated factors influencing central AP in uni- and multivariate linear regression analyses and age-related change in central AP using the Mobil-O-Graph in healthy Japanese individuals.</p><p><strong>Results: </strong>Central AP were lower in men than in women (5.5 ± 2.8 vs. 11.0 ± 4.7 mm Hg, <i>p</i> < 0.001). The central AP in the total cohort was positively correlated with age (<i>r</i> = 0.325, <i>p</i> < 0.001) and inversely correlated with height (<i>r</i> = -0.601, <i>p</i> < 0.001) in the Pearson correlations. In multivariate regression analysis, the parameters influencing central AP (<i>R</i>>sup<2>/sup< = 0.467) were age (β = 0.097, <i>p</i> < 0.001), sex (β = -2.890, <i>p</i> = 0.010), and height (β = -0.153, <i>p</i> = 0.031). The central AP (10.0 ± 4.8 mm Hg) in the ≥50-year-old group significantly increased compared with those in the 20- to 39-year-old group (6.7 ± 4.2 mm Hg, <i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>Age, sex, and height influenced central AP, as assessed using the Mobil-O-Graph. Age-related increase in central AP was observed in normotensive Japanese individuals. Brachial cuff-based waveform recordings using the Mobil-O-Graph are feasible for the estimation of central AP in the Asian population.</p>\",\"PeriodicalId\":29774,\"journal\":{\"name\":\"Pulse\",\"volume\":\"6 3-4\",\"pages\":\"161-168\"},\"PeriodicalIF\":7.3000,\"publicationDate\":\"2019-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1159/000496151\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pulse\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000496151\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2019/1/30 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"PERIPHERAL VASCULAR DISEASE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pulse","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000496151","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2019/1/30 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}
引用次数: 2
摘要
背景:近年来，人们开发了一种利用振荡袖带从肱血压波形中提取中枢血压(BP)波形的装置。中央区收缩压后期升高是中央区血流动力学的标志。mobilo - graph是一种基于袖带的振荡测量装置，可以评估中心增强压力(AP)和中心BP。据报道，在欧洲人群中使用mobile - o - graph测量中心AP与年龄和性别有关。然而，影响亚洲人群中央区AP的因素尚未得到证实。目的和方法:我们招募了110名血压正常的志愿者(50名男性;年龄范围:21-76岁)。休息至少5分钟后，受试者保持坐姿，使用左手臂上的移动- o - graph测量中央血压和AP。我们比较了两性之间的中央血流动力学。我们通过单因素和多因素线性回归分析研究了影响中心AP的因素，并利用日本健康个体的mobile - o - graph研究了中心AP的年龄相关变化。结果:男性中枢性AP低于女性(5.5±2.8 vs 11.0±4.7 mm Hg, p < 0.001)。在Pearson相关性中，总队列中心AP与年龄呈正相关(r = 0.325, p < 0.001)，与身高呈负相关(r = -0.601, p < 0.001)。多因素回归分析中，影响中心AP (R>sup/sup< = 0.467)的参数为年龄(β = 0.097, p< 0.001)、性别(β = -2.890, p = 0.010)和身高(β = -0.153, p = 0.031)。≥50岁组中枢性AP(10.0±4.8 mm Hg)明显高于20 ~ 39岁组(6.7±4.2 mm Hg, p < 0.05)。结论:年龄、性别和身高影响中心AP，通过mobile - o - graph进行评估。在血压正常的日本个体中观察到与年龄相关的中心性AP增高。使用mobile - o - graph的基于臂袖的波形记录对于估计亚洲人群的中心AP是可行的。
Cuff-Based Oscillometric Measurements of Central Hemodynamics: Factors Influencing Central Augmentation Pressure in Normotensive Japanese Individuals.
Background: Recently, new devices using oscillometric cuff have been developed to derive central blood pressure (BP) waveform from brachial BP waveform. Late systolic pressure augmentation of central BP waveform is a marker of central hemodynamics. Mobil-O-Graph, a cuff-based oscillometric device, can assess central augmentation pressure (AP) together with central BP. Central AP measurement using the Mobil-O-Graph in the European population was reported to be associated with age and sex. However, factors influencing central AP in the Asian population have not been shown.
Objectives and methods: We enrolled 110 normotensive volunteers (50 men; age range, 21‒76 years). Central BP and AP were measured using the Mobil-O-Graph on the left arm with the subjects in the seated position after resting for at least 5 min. We compared central hemodynamics between the sexes. We investigated factors influencing central AP in uni- and multivariate linear regression analyses and age-related change in central AP using the Mobil-O-Graph in healthy Japanese individuals.
Results: Central AP were lower in men than in women (5.5 ± 2.8 vs. 11.0 ± 4.7 mm Hg, p < 0.001). The central AP in the total cohort was positively correlated with age (r = 0.325, p < 0.001) and inversely correlated with height (r = -0.601, p < 0.001) in the Pearson correlations. In multivariate regression analysis, the parameters influencing central AP (R>sup<2>/sup< = 0.467) were age (β = 0.097, p < 0.001), sex (β = -2.890, p = 0.010), and height (β = -0.153, p = 0.031). The central AP (10.0 ± 4.8 mm Hg) in the ≥50-year-old group significantly increased compared with those in the 20- to 39-year-old group (6.7 ± 4.2 mm Hg, p < 0.05).
Conclusions: Age, sex, and height influenced central AP, as assessed using the Mobil-O-Graph. Age-related increase in central AP was observed in normotensive Japanese individuals. Brachial cuff-based waveform recordings using the Mobil-O-Graph are feasible for the estimation of central AP in the Asian population.
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