非洲的非酒精性脂肪肝:隐藏的危险。

IF 1.1 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Global Health Epidemiology and Genomics Pub Date : 2019-04-12 eCollection Date: 2019-01-01 DOI:10.1017/gheg.2019.2
Imran M Paruk, Fraser J Pirie, Ayesha A Motala
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引用次数: 0

摘要

有关非酒精性脂肪肝(NAFLD)在非洲人口中的负担和范围的数据十分匮乏。现有的有限信息表明,非洲地区非酒精性脂肪肝在普通人群中的发病率最低。然而,这很可能是一种低估,而且也没有考虑到非洲肥胖症、2 型糖尿病(T2DM)发病率上升和人类免疫缺陷病毒感染率高所带来的长期影响。一些研究发现,非酒精性脂肪肝的患病率存在种族差异,但原因不明。非洲缺乏以人口为基础的研究数据,这凸显了开展此类研究的必要性,以便可靠地确定该地区的医疗服务需求。对于资源匮乏的地区来说,利用超声波在人群中筛查非酒精性脂肪肝也许是最理想的方法,因为它具有相对的成本效益。非洲的当务之急是开展精心设计的流行病学研究,在普通人群以及高危人群(如 T2DM 或肥胖症患者)中筛查非酒精性脂肪肝。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Non-alcoholic fatty liver disease in Africa: a hidden danger.

Non-alcoholic fatty liver disease in Africa: a hidden danger.

There is a dearth of data on the burden and spectrum of non-alcoholic fatty liver disease (NAFLD) in African populations. The limited available information suggests that the prevalence of NAFLD in the general population is lowest for the Africa region. However, this is likely to be an underestimate and also does not take into consideration the long-term impact of rising rates of obesity, type-2 diabetes mellitus (T2DM) and high human immunodeficiency virus infection burden in Africa. A racial disparity in the prevalence of NAFLD has been observed in some studies but remains unexplained. There is an absence of data from population-based studies in Africa and this highlights the need for such studies, to reliably define the health service needs for this region. Screening for NAFLD at a population-based level using ultrasound is perhaps the ideal method for resource-poor settings because of its relative cost-effectiveness. What is required as a priority from Africa, are well-designed epidemiologic studies that screen for NAFLD in the general population as well as high-risk groups such as patients with T2DM or obesity.

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来源期刊
Global Health Epidemiology and Genomics
Global Health Epidemiology and Genomics PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
1.40
自引率
0.00%
发文量
10
审稿时长
20 weeks
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