粪便钙保护蛋白在儿科疾病中的作用。

Korean Journal of Pediatrics Pub Date : 2019-08-01 Epub Date: 2019-03-28 DOI:10.3345/kjp.2019.00059

Su Jin Jeong

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引用次数: 15

摘要

粪钙保护蛋白(FC)是一种S100家族的钙锌结合蛋白，主要由中性粒细胞表达，在炎症过程中释放。对于胃肠病学家和全科医生来说，FC越来越成为区分炎症性肠病(IBD)和肠易激综合征的有用工具。越来越多的证据支持使用这种生物标志物来诊断、随访和评估几种儿科胃肠道疾病的治疗反应，从IBD到非特异性结肠炎和坏死性小肠结肠炎。本文综述了目前关于FC在临床应用的文献。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

The role of fecal calprotectin in pediatric disease.

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The role of fecal calprotectin in pediatric disease.

Fecal calprotectin (FC) is a calcium- and zinc-binding protein of the S100 family, mainly expressed by neutrophils and released during inflammation. FC became an increasingly useful tool both for gastroenterologists and for general practitioners for distinguishing inflammatory bowel disease (IBD) from irritable bowel syndrome. Increasing evidences support the use of this biomarker for diagnosis, follow-up and evaluation of response to therapy of several pediatric gastrointestinal diseases, ranging from IBD to nonspecific colitis and necrotizing enterocolitis. This article summarizes the current literature on the use of FC in clinical practice.

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来源期刊

Korean Journal of Pediatrics

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： Korean J Pediatr covers clinical and research works relevant to all aspects of child healthcare. The journal aims to serve pediatricians through the prompt publication of significant advances in any field of pediatrics and to rapidly disseminate recently updated knowledge to the public. Additionally, it will initiate dynamic, international, academic discussions concerning the major topics related to pediatrics. Manuscripts are categorized as review articles, original articles, and case reports. Areas of specific interest include: Growth and development, Neonatology, Pediatric neurology, Pediatric nephrology, Pediatric endocrinology, Pediatric cardiology, Pediatric allergy, Pediatric pulmonology, Pediatric infectious diseases, Pediatric immunology, Pediatric hemato-oncology, Pediatric gastroenterology, Nutrition, Human genetics, Metabolic diseases, Adolescence medicine, General pediatrics.