[Treatment of Idiopathic Thrombocytopenic Purpura by Xiaoban Decoction: a Case Observation of 119 Patients].

Objective To observe the clinical effect of Xiaoban Decoction (XBD) in treating idio- pathic thrombocytopenic purpura (ITP). Methods Totally 119 ITP patients were treated by XBD. The he- mogram, bleeding symptoms, effective rate, and adverse reactions were observed before and after treatment. Patient condition was observed while taking XBD but with other treatment program withdrawal (including glucocorticoids). Results After 6 -18 months of treatment, WBC count, hemoglobin concen- tration, and platelet count were all increased, as compared before treatment. Complete relief (CR) oc- curred in 57 cases (platelet count≥100 x10⁹/L) , response(R) in 27 cases (platelet count≥50 x10⁹/L) , no relief (NR) in 35 cases (platelet count <50 x10⁹/L). The total effective rate was 70. 6%. Bleeding symptoms were improved after one-month treatment. There were 70 patients using glucocorticoids before taking XBD. No withdrawal crisis occurred after rapid withdrawal. No adverse reaction occurred, except increased times of passing stool. Seven patients were pregnant during follow-up and gave birth safely lat- er. Conclusions XBD, independent of glucocorticoids, could rapidly improve bleeding symptoms and steadily elevate platelet count. It was an effectively long-lasting treatment of Chinese medicine.