超声心动图评价心包脂肪组织厚度与早期左心室功能损害的关系。

Aeka Fujino, Tomonori Kishino, Keiko Watanabe, Kumiko Sekiguchi, Yasushi Takagi, Satsuki Matsushima, Kouki Ohtsuka, Masayuki Yotsukura, Hiroaki Ohnishi, Takashi Watanabe
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引用次数: 0

摘要

心外膜脂肪组织(EAT)具有代谢生物活性,该组织的积累与左心室(LV)收缩功能和舒张功能的早期损害有关。然而,位于EAT外的心包脂肪组织(PAT)最近被证明与代谢危险因素的关系比EAT更密切。本研究旨在通过超声心动图评估PAT厚度是否与早期左室功能损害相关,其方式与EAT厚度相似。受试者为49名女性,平均年龄68岁,既有代谢性疾病患者,也有其他疾病患者,射血分数(EF) >55%。通过测量EF、收缩二尖瓣环速度(S')和组织二尖瓣环位移百分比(TMAD%)来评估收缩功能。通过测量心房收缩引起的早期快速充盈波速度(E)/晚期充盈波速度(A)比(E/A)、舒张早期尖峰二尖瓣环速度(E′)和E/ E′比来评估舒张功能。评估EAT或PAT厚度与左室收缩或舒张功能的相关性。EAT厚度与S′和TMAD%相关(r=-0.399, p=0.005和r=-0.570, p= 0.05)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Relationship between Pericardial Adipose Tissue Thickness and Early Impairment of Left Ventricular Function, Both Evaluated on Echocardiography.

Epicardial adipose tissue (EAT) is metabolically bioactive, and accumulation of this tissue is related to early impairment of left ventricular (LV) systolic function as well as diastolic function. However, pericardial adi- pose tissue (PAT), located outside the EAT, has recently been demonstrated to be more closely associated with metabolic risk factors than EAT. The present study aimed to clarify whether PAT thickness is related to early impairment of LV function in a similar manner to EAT thickness, with both evaluated echocardio- graphically. Subjects were 49 women (mean age, 68ill years) composed of both patients with metabolic diseases and those with other diseases, and ejection fraction (EF) >55%. Systolic function was assessed by measuring EF, systolic mitral annular velocity (S'), and tissue mitral annular displacement percentage (TMAD%). Diastolic function was assessed by measuring early rapid filling wave velocity (E)/late filling wave velocity due to atrial contraction (A) ratio (E/A), peak early diastolic mitral annular velocity (e'), and E/e' ratio. Correlations between EAT or PAT thickness and LV systolic or diastolic function were assessed. EAT thickness correlated with S' and TMAD%(r=-0.399, p=0.005 and r=-0.570, p<0.001, respective- ly), but not with EF. However, PAT thickness was not correlated with any of these. EAT thickness corre- lated with E/A, e' and E/e'(r=-0.382, p=0.007; r=-0.493, p<0.001; and r=0.331, p=0.020, respective- ly). Again, PAT thickness was not correlated with any of these. PAT thickness appears unrelated to early impairment of LV function.

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