{"title":"IL-4基因C-590T等位基因多态性是儿童急性阻塞性支气管炎复发易感性的最可能的遗传标记。","authors":"O Kens, N Vishtak, H Acopyan, V Bergtravm","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Molecular-genetic study of C-590T polymorphic locus of IL-4 gene in 31 children with recurrent episodes of acute obstructive bronchitis and 50 people who constituted the control population-based group has been carried out. It is proved that the presence of this polymorphic locus leads to three-fold increase of the risk of acute obstructive bronchitis recurrent episodes.</p>","PeriodicalId":23230,"journal":{"name":"TSitologiia i genetika","volume":"50 3","pages":"30-5"},"PeriodicalIF":0.0000,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Allelic polymorphism C-590T of the gene IL-4 as the most possible genetic marker of high predisposition to development of recurrent episodes of acute obstructive bronchitis in children.\",\"authors\":\"O Kens, N Vishtak, H Acopyan, V Bergtravm\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Molecular-genetic study of C-590T polymorphic locus of IL-4 gene in 31 children with recurrent episodes of acute obstructive bronchitis and 50 people who constituted the control population-based group has been carried out. It is proved that the presence of this polymorphic locus leads to three-fold increase of the risk of acute obstructive bronchitis recurrent episodes.</p>\",\"PeriodicalId\":23230,\"journal\":{\"name\":\"TSitologiia i genetika\",\"volume\":\"50 3\",\"pages\":\"30-5\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"TSitologiia i genetika\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"TSitologiia i genetika","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Allelic polymorphism C-590T of the gene IL-4 as the most possible genetic marker of high predisposition to development of recurrent episodes of acute obstructive bronchitis in children.
Molecular-genetic study of C-590T polymorphic locus of IL-4 gene in 31 children with recurrent episodes of acute obstructive bronchitis and 50 people who constituted the control population-based group has been carried out. It is proved that the presence of this polymorphic locus leads to three-fold increase of the risk of acute obstructive bronchitis recurrent episodes.
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