中部地区2013-2014年铜绿假单胞菌对几种抗菌药物的敏感性监测

The Japanese journal of antibiotics Pub Date : 2016-10-01
Ai Kakumoto, Hayato Okade, Junichi Misuyama, Kazukiyo Yamaoka, Yuko Asano, Yoko Matsukawa, Hiroyuki Suematsu, Haruki Sawamura, Shigenori Matsubara, Naohiro Shibata, Kunitomo Watanabe, Yoshihiro Yamamoto, Hiromichi Iwasaki, Yuka Yamagishi, Hiroshige Mikamo
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引用次数: 0

摘要

对2013年10月至2014年2月在岐阜县、爱知县、富山县和福井县医疗机构分离的186株铜绿假单胞菌临床分离株进行抗菌药物敏感性调查。哌拉西林(PIPC),他唑巴坦/哌拉西林(TAZ/PIPC),头孢他啶(CAZ),头孢吡肟(CFPM),亚胺培南(IPM),美罗培南(MEPM),多利培南(DRPM),氮曲南(AZT),环丙沙星(CPFX),左氧氟沙星(LVFX),阿米卡星(AMK)和粘菌素(CL)对铜绿假单胞菌的MIC₅₀/₉₀分别为8/ 32,4 / 32,2 / 8,2 /16,1/32,0.5/ 8,0.25 / 4,8 /32,0.25/ 8,0.5 /16,4/8和1/1pg/ ml。分离到2株多重耐药铜绿假单胞菌(1.1%)。他们从呼吸道、腹腔和泌尿系统感染中分离出来。腹腔感染对碳青霉烯类铜绿假单胞菌的敏感率低于呼吸道感染和泌尿系统感染。泌尿系感染对青霉素、头孢菌素、单巴坦和氟喹诺酮类药物的敏感率低于呼吸道感染和腹腔感染。关注感染器官各临床标本对抗菌药物的敏感性具有重要意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Sensitivity surveillance of Pseudomonas aeruginosa isolates for several antibacterial agents in Chubu area (2013-2014).

We investigated the susceptibility to antibacterial agents of 186 clinical isolates of Pseudomonas aeruginosa isolated from medical facilities in Gifu, Aichi, Toyama, and Fukui prefectures from October 2013 to February 2014. MIC₅₀/₉₀ of piperacillin (PIPC), tazobactam/piperacillin (TAZ/PIPC), ceftazidime (CAZ), cefepime (CFPM), imipenem (IPM), meropenem (MEPM), doripenem (DRPM), aztreonam (AZT), ciprofloxacin (CPFX), levofloxacin (LVFX), amikacin (AMK) and colistin (CL) against P aeruginosa was 8/32, 4/32, 2/8, 2/16, 1/32, 0.5/8, 0.25/4, 8/32, 0.25/8, 0.5/16, 4/8 and 1/1pg/mLrespectively. Two strains of multidrug resistant P aeruginosa were isolated (1.1%). They were isolated from the respiratory tract, intra-abdominal, and urinary infection. The susceptible ratio against P aeruginosa derived from intra-abdominal infection for carbapenem was lower than those from respiratory tract and urinary infection. The susceptible ratio against P aeruginosa derived from urinary infection for penicillin, cephem, monobactam, and fluoroquinolone was lower than those from respiratory and intra-abdominal infection. It is meaningful to pay attention to the susceptibility to antibacterial agents in each clinical specimen from infected organ.

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