心肌功能指数作为超声心动图预测首次急性st段抬高型心肌梗死早期院内心力衰竭的指标

IF 1.4 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Hossamaldin Zaki Alsayed Abuomara, Ossama Mohamed Hassan, Tarek Rashid, Mahmoud Baraka
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引用次数: 8

摘要

目的探讨心肌表现指数(MPI)作为超声心动图预测急性st段抬高型心肌梗死(STEMI)早期院内心力衰竭(HF)的价值。背景:心肌梗死可引起不同程度的左心室收缩和舒张功能损害。射血分数(EF)和透射血流分别是评估收缩期和舒张期功能最常用的方法,两者都有相当大的局限性。MPI是一个单一参数,能够估计收缩期和舒张期的综合表现,缺乏这样的局限性。方法:我们招募了60例首次出现急性前路STEMI的患者,并接受了初级PCI治疗。在胸痛后24 h内进行超声心动图检查并测量MPI。左室MPI计算为(等容收缩时间“ICT”+松弛时间“IRT”)/射血时间“ET”。此外,分析临床和超声心动图变量,将CHF定义为Killip级 ≥ II。结果23例患者(38%)发生院内早期心衰。射血分数与院内HF的发生呈极显著负相关(p = .0001),而MPI与院内HF的发生呈极显著正相关(p = .0001)。MPI的截断点 > 0.73显示了识别HF患者的非常高的特异性(94.6%)和敏感性(78.3%)。另一方面,EF ≤ 33%的截断点对HF预测的特异性为94.6%,敏感性为56.5%。结论MPI可能是首次急性前路STEMI后院内HF的重要预测因子。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Myocardial performance index as an echocardiographic predictor of early in-hospital heart failure during first acute anterior ST-elevation myocardial infarction

Myocardial performance index as an echocardiographic predictor of early in-hospital heart failure during first acute anterior ST-elevation myocardial infarction

Myocardial performance index as an echocardiographic predictor of early in-hospital heart failure during first acute anterior ST-elevation myocardial infarction

Myocardial performance index as an echocardiographic predictor of early in-hospital heart failure during first acute anterior ST-elevation myocardial infarction

Objectives

To determine the value of Myocardial Performance Index (MPI) as an echocardiographic predictor of early in-hospital heart failure (HF) during first acute anterior ST-Elevation Myocardial Infarction (STEMI).

Background

Myocardial infarction induces variable degrees of impairment in left ventricular (LV) systolic and diastolic functions. The ejection fraction (EF) and transmitral flow, the most frequently used methods for evaluation of systolic and diastolic functions respectively, both have considerable limitations. The MPI is a single parameter, capable of estimating combined systolic and diastolic performance and lacks such limitations.

Methods

We enrolled 60 patients presented with a first acute anterior STEMI who have undergone primary PCI. Echocardiography was done within 24 h of chest pain with measurement of MPI. The LV MPI was calculated as (isovolumic contraction time “ICT” + relaxation time “IRT”)/Ejection time “ET”. Besides, clinical and echocardiographic variables were analyzed and CHF was defined as Killip class ≥ II.

Results

Early in-hospital HF occurred in 23 of patients (38%). Ejection fraction was found to have a highly significant negative correlation with the development of in-hospital HF (p = .0001), while MPI was found to have a highly significant positive correlation (p = .0001). A cut-off point of MPI > 0.73 showed a very high specificity (94.6%) and sensitivity (78.3%) for identifying patients with HF. On the other hand, a cut-off point of EF ≤ 33% has shown 94.6% specificity and 56.5% sensitivity for HF prediction.

Conclusions

The MPI might be a strong predictor of in-hospital HF after first acute anterior STEMI.

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来源期刊
Egyptian Heart Journal
Egyptian Heart Journal CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
2.10
自引率
0.00%
发文量
82
审稿时长
9 weeks
期刊介绍: The Egyptian Heart Journal is the official journal of the Egyptian Society of Cardiology. It is an international journal that publishes peer-reviewed articles on all aspects of cardiovascular disease, including original clinical studies and translational investigations. The journal publishes research, review articles, case reports and commentary articles, as well as editorials interpreting and commenting on the research presented. In addition, it provides a forum for the exchange of information on all aspects of cardiovascular medicine, including educational issues.
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