{"title":"睡眠和睡眠障碍的神经生物学基础。","authors":"William J Joiner","doi":"10.1152/physiol.00013.2018","DOIUrl":null,"url":null,"abstract":"<p><p>The functions of sleep remain a mystery. Yet they must be important since sleep is highly conserved, and its chronic disruption is associated with various metabolic, psychiatric, and neurodegenerative disorders. This review will cover our evolving understanding of the mechanisms by which sleep is controlled and the complex relationship between sleep and disease states.</p>","PeriodicalId":520753,"journal":{"name":"Physiology (Bethesda, Md.)","volume":" ","pages":"317-327"},"PeriodicalIF":10.3000,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1152/physiol.00013.2018","citationCount":"23","resultStr":"{\"title\":\"The Neurobiological Basis of Sleep and Sleep Disorders.\",\"authors\":\"William J Joiner\",\"doi\":\"10.1152/physiol.00013.2018\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The functions of sleep remain a mystery. Yet they must be important since sleep is highly conserved, and its chronic disruption is associated with various metabolic, psychiatric, and neurodegenerative disorders. This review will cover our evolving understanding of the mechanisms by which sleep is controlled and the complex relationship between sleep and disease states.</p>\",\"PeriodicalId\":520753,\"journal\":{\"name\":\"Physiology (Bethesda, Md.)\",\"volume\":\" \",\"pages\":\"317-327\"},\"PeriodicalIF\":10.3000,\"publicationDate\":\"2018-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1152/physiol.00013.2018\",\"citationCount\":\"23\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Physiology (Bethesda, Md.)\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1152/physiol.00013.2018\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physiology (Bethesda, Md.)","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1152/physiol.00013.2018","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The Neurobiological Basis of Sleep and Sleep Disorders.
The functions of sleep remain a mystery. Yet they must be important since sleep is highly conserved, and its chronic disruption is associated with various metabolic, psychiatric, and neurodegenerative disorders. This review will cover our evolving understanding of the mechanisms by which sleep is controlled and the complex relationship between sleep and disease states.