胆汁酸在非酒精性脂肪肝和2型糖尿病患者脂质和碳水化合物代谢调节中的作用

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01

L A Zvenigorodskaya, A V Petrakov, T V Nilova, G G Varvanina, A E Lychkova

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引用次数: 0

摘要

胆汁酸调节葡萄糖和脂质代谢。目的:NAFLD合并2型糖尿病患者血清总胆汁酸的测定。测定炎症标志物(一氧化氮、内毒素、磷脂酶A2、丙二醛)对胆汁酸合成和转运的影响作用。NAFLD合并2型糖尿病患者胆汁酸的合成和运输中断减少，这与酶系统抑制和炎症引起的细胞膜损伤有关。

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THE ROLE OF BILE ACIDS IN THE REGULATION OF LIPID AND CARBOHYDRATE METABOLISM IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE AND DIABETES TYPE2.

Bile acids regulate glucose and lipid metabolism. Aim -determination of total serum bile acids in patients with NAFLD and in combination with type 2 diabetes. To determine the inflammatory markers (nitric oxide, endotoxin, phospholipase A2, malondialdehyde) effects role for the synthesis and transport of bile acids. NAFLD patients with type 2 diabetes observed decrease in synthesis and disruption of transport of bile acids, which is associated with the cell membrane damage by inhibition of enzyme systems, and inflammation.

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Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology

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