{"title":"[急性意外“poppres”中毒引起的高铁血红蛋白血症-一例报告]。","authors":"Daria Schetz, Wojciech Waldman, Jacek Sein Anand","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Recently we observe an increase in\nthe number of intoxications due to xenobiotics\nthat may induce acute methemoglobinemia.\nOur study showed a\ncase of acute methemoglobinemia\n(MetHb 55..2%) in 25 – year old man.\nClinical symptoms were caused by ingestion\nof “poppers” which was used\nby patient as “aphrodisiac”. Summary:\nConclusions: 1. Oral intake of alkyl nitrites,\nincluding isobutyl nitrite, is burdened\nwith the risk of life-threatening\nmethemoglobinemia . 2. In the case of\npoisonings running with normal pO2,\nreduced level of oxygen saturation,\nclinical signs of cyanosis does not react\nto oxygen therapy, and “chocolate”\ntinge of blood methemoglobinemia\nshould be suspected. 3. In every case\nof MetHb the use of antidote, which is\nmethylene blue, should be considered.\n4. The severity of cyanosis correlates\nwith the level of methemoglobin.</p>","PeriodicalId":21148,"journal":{"name":"Przeglad lekarski","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Methemoglobinemia as a result of acute accidental “poppres” poisoning – a case report].\",\"authors\":\"Daria Schetz, Wojciech Waldman, Jacek Sein Anand\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Recently we observe an increase in\\nthe number of intoxications due to xenobiotics\\nthat may induce acute methemoglobinemia.\\nOur study showed a\\ncase of acute methemoglobinemia\\n(MetHb 55..2%) in 25 – year old man.\\nClinical symptoms were caused by ingestion\\nof “poppers” which was used\\nby patient as “aphrodisiac”. Summary:\\nConclusions: 1. Oral intake of alkyl nitrites,\\nincluding isobutyl nitrite, is burdened\\nwith the risk of life-threatening\\nmethemoglobinemia . 2. In the case of\\npoisonings running with normal pO2,\\nreduced level of oxygen saturation,\\nclinical signs of cyanosis does not react\\nto oxygen therapy, and “chocolate”\\ntinge of blood methemoglobinemia\\nshould be suspected. 3. In every case\\nof MetHb the use of antidote, which is\\nmethylene blue, should be considered.\\n4. The severity of cyanosis correlates\\nwith the level of methemoglobin.</p>\",\"PeriodicalId\":21148,\"journal\":{\"name\":\"Przeglad lekarski\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Przeglad lekarski\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Przeglad lekarski","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Methemoglobinemia as a result of acute accidental “poppres” poisoning – a case report].
Recently we observe an increase in
the number of intoxications due to xenobiotics
that may induce acute methemoglobinemia.
Our study showed a
case of acute methemoglobinemia
(MetHb 55..2%) in 25 – year old man.
Clinical symptoms were caused by ingestion
of “poppers” which was used
by patient as “aphrodisiac”. Summary:
Conclusions: 1. Oral intake of alkyl nitrites,
including isobutyl nitrite, is burdened
with the risk of life-threatening
methemoglobinemia . 2. In the case of
poisonings running with normal pO2,
reduced level of oxygen saturation,
clinical signs of cyanosis does not react
to oxygen therapy, and “chocolate”
tinge of blood methemoglobinemia
should be suspected. 3. In every case
of MetHb the use of antidote, which is
methylene blue, should be considered.
4. The severity of cyanosis correlates
with the level of methemoglobin.