玻璃体部切除联合内限制膜剥离治疗非牵引性糖尿病黄斑水肿。

IF 0.4 Q4 OPHTHALMOLOGY
Open Ophthalmology Journal Pub Date : 2017-01-31 eCollection Date: 2017-01-01 DOI:10.2174/1874364101711010005
Jan Niklas Ulrich
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引用次数: 12

摘要

背景:糖尿病仍然是美国工作年龄人群致盲的主要原因,糖尿病性黄斑水肿是导致中度和重度视力丧失的最常见原因。目的:探讨非牵引性糖尿病性黄斑水肿患者行玻璃体切割合并内限制膜剥离术的解剖学和视觉效果,以及光谱域光学相干断层扫描视网膜外层完整性与视觉效果的相关性。方法:回顾性分析42例非牵引性糖尿病黄斑水肿行玻璃体切除术合并内限制膜剥离的糖尿病患者的病历。评估视网膜外层的完整性,并与术后1个月、3个月、6个月的资料比较术前黄斑中央厚度和视力。采用学生t检验进行组间比较。结果:纳入31只眼。虽然在1个月和3个月时没有观察到差异,但在6个月的随访中,与术前相比,中央黄斑厚度和视力都有显著改善(357,427微米;p = 0.03。20/49, 20/82;p = 0.03)。外限制膜和椭球带完整的患者术前视力优于视网膜外层不规则的患者(20/ 54,20 /100;P =0.03),术后视力明显提高(20/33,20/81;p =非重要)。结论:非牵引性糖尿病黄斑水肿患者行玻璃体切除联合内限制膜剥离可改善视网膜解剖结构和视力。光谱域光学相干断层扫描可以帮助识别有视力改善潜力的患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Pars Plana Vitrectomy with Internal Limiting Membrane Peeling for Nontractional Diabetic Macular Edema.

Pars Plana Vitrectomy with Internal Limiting Membrane Peeling for Nontractional Diabetic Macular Edema.

Background: Diabetes mellitus remains the leading cause of blindness among working age Americans with diabetic macular edema being the most common cause for moderate and severe vision loss.

Objective: To investigate the anatomical and visual benefits of pars plana vitrectomy with inner limiting membrane peeling in patients with nontractional diabetic macular edema as well as correlation of integrity of outer retinal layers on spectral domain optical coherence tomography to visual outcomes.

Methods: We retrospectively reviewed the charts of 42 diabetic patients that underwent vitrectomy with internal limiting membrane peeling for nontractional diabetic macula edema. The integrity of outer retinal layers was evaluated and preoperative central macular thickness and visual acuity were compared with data at 1 month, 3 months and 6 months postoperatively. The student t-test was used to compare the groups.

Results: 31 eyes were included. While no differences were seen at 1 and 3 months, there was significant improvement of both central macular thickness and visual acuity at the 6 months follow up visit compared to preoperatively (357, 427 microns; p=0.03. 20/49, 20/82; p=0.03) . Patients with intact external limiting membrane and ellipsoid zone had better preoperative vision than patients with outer retinal layer irregularities (20/54, 20/100; p=0.03) and greater visual gains postoperatively (20/33, p<0.001 versus 20/81; p=non-significant).

Conclusion: Pars plana vitrectomy with internal limiting membrane peeling can improve retinal anatomy and visual acuity in patients with nontractional diabetic macular edema. Spectral domain optical coherence tomography may help identify patients with potential for visual improvement.

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来源期刊
CiteScore
0.50
自引率
0.00%
发文量
24
期刊介绍: The Open Ophthalmology Journal is an Open Access online journal, which publishes research articles, reviews/mini-reviews, letters and guest edited single topic issues in all important areas of experimental and clinical research in ophthalmology, including use of ophthalmological therapies, devices and surgical techniques. The Open Ophthalmology Journal, a peer-reviewed journal, is an important and reliable source of current information on developments in the field. The emphasis will be on publishing quality papers rapidly and making them freely available to researchers worldwide.
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