乳糜腹水:评估和管理。

ISRN hepatology Pub Date : 2014-02-03 eCollection Date: 2014-01-01 DOI:10.1155/2014/240473
Said A Al-Busafi, Peter Ghali, Marc Deschênes, Philip Wong
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引用次数: 121

摘要

乳糜腹水是指由于创伤性损伤或梗阻引起的淋巴系统破坏而导致的富脂淋巴在腹膜腔内的积聚。在世界范围内,腹部恶性肿瘤、肝硬化和肺结核是成人CA最常见的病因,后者在发展中国家最为普遍,而先天性淋巴系统异常和创伤在儿童中最为常见。乳白色、奶油状的腹水,甘油三酯含量超过200 mg/dL是诊断性的,在大多数情况下,除非有强烈的恶性怀疑,否则肝硬化患者不需要进一步检查。如果确定了潜在的原因,靶向治疗是可能的,但大多数病例将保守治疗,饮食支持包括高蛋白和低脂饮食,补充中链甘油三酯,治疗性穿刺,全肠外营养和生长抑素。很少有耐药病例采用经颈静脉肝内门静脉分流术、手术探查或腹膜静脉分流术治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Chylous Ascites: Evaluation and Management.

Chylous Ascites: Evaluation and Management.

Chylous ascites refers to the accumulation of lipid-rich lymph in the peritoneal cavity due to disruption of the lymphatic system secondary to traumatic injury or obstruction. Worldwide, abdominal malignancy, cirrhosis, and tuberculosis are the commonest causes of CA in adults, the latter being most prevalent in developing countries, whereas congenital abnormalities of the lymphatic system and trauma are commonest in children. The presence of a milky, creamy appearing ascitic fluid with triglyceride content above 200 mg/dL is diagnostic, and, in the majority of cases, unless there is a strong suspicion of malignancy, further investigations are not required in patients with cirrhosis. If an underlying cause is identified, targeted therapy is possible, but most cases will be treated conservatively, with dietary support including high-protein and low-fat diets supplemented with medium-chain triglycerides, therapeutic paracentesis, total parenteral nutrition, and somatostatins. Rarely, resistant cases have been treated by transjugular intrahepatic portosystemic shunt, surgical exploration, or peritoneovenous shunt.

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