重组细胞因子的植物生产者(综述)。

M S Burlakovskii, V V Yemel'yanov, L A Lutova
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引用次数: 0

摘要

细胞因子是一个信号多肽家族,参与免疫反应过程中细胞与细胞的相互作用,以及一些正常生理功能的调节。细胞因子在医学上用于治疗癌症、免疫紊乱、病毒感染和其他具有社会意义的疾病,但其使用的程度受到活性物质的高生产成本的限制。这一药理学领域的发展与基因工程的成功有关,基因工程允许转基因生物生产大量蛋白质。本文综述了利用转基因植物生产各种细胞因子的最新进展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Plant-Producers Of Recombinant Cytokines (Review)].

Cytokines are a family of signaling polypeptides involved in cell-cell interactions in the process of the immune response, as well as in the regulation of a number of normal physiological functions. Cytokines are used in medicine for the treatment of cancer, immune disorders, viral infections, and other socially significant diseases, but the extent of their use is limited by the high production cost of the active agent. The development of this area of pharmacology is associated with the success of genetic engineering, which allows the production of significant amounts of protein by transgenic organisms. The review discusses the latest advances in the production of various cytokines with the use of genetically modified plants.

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