局部钙调磷酸酶抑制剂的标签外使用。

Q1 Medicine

Skin therapy letter Pub Date : 2016-01-01

E Wong, A Kurian

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引用次数: 0

摘要

局部钙调磷酸酶抑制剂(tci)已被提出作为局部皮质类固醇的替代长期治疗选择，没有类固醇使用通常相关的副作用。目前，tci仅被批准用于治疗2岁及以上患者的特应性皮炎。本文综述了tci的超说明书使用及其在皮肤疾病治疗中的疗效。研究表明，tci可能对治疗/管理各种皮肤状况有效。对临床结果最有力的证据支持已报道过敏性接触性皮炎、扁平苔藓、牛皮癣、脂溢性皮炎和白癜风。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Off-Label Uses of Topical Calcineurin Inhibitors.

Topical calcineurin inhibitors (TCIs) have been proposed as an alternative, long-term treatment option to topical corticosteroids, without the side effects commonly associated with steroid use. Currently, TCIs are only approved for treatment of atopic dermatitis in patients 2 years of age or older. This article reviews the off-label uses of TCIs and their efficacy in the treatment of cutaneous diseases. Studies show that TCIs may be effective in treating/managing a variety of skin conditions. The strongest evidence based support on clinical outcomes has been reported for allergic contact dermatitis, lichen planus, psoriasis, seborrheic dermatitis and vitiligo.

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来源期刊

Skin therapy letter Medicine-Medicine (all)

CiteScore

2.80

自引率

0.00%

发文量

期刊介绍： The premier international journal on the latest advances, techniques and practice in conservation and restoration from around the world.