油橄榄生物合成银纳米颗粒的优化、表征及抗癌潜力。

IF 3 Q3 MATERIALS SCIENCE, BIOMATERIALS
International Journal of Biomaterials Pub Date : 2022-09-26 eCollection Date: 2022-01-01 DOI:10.1155/2022/6859637
Afnan I Felimban, Njud S Alharbi, Nehad S Alsubhi
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引用次数: 2

摘要

绿色合成作为一种环保、低成本、高能效和无毒的制备纳米银纳米粒子(AgNPs)的方法受到了广泛的关注。本研究优化了油橄榄提取物绿色合成AgNPs的工艺,并对其抗癌潜力进行了评价。采用多种方法对生物合成的AgNPs进行了表征,结果表明AgNPs具有良好的形态和高产率,从而提高了AgNPs的各种药用性能。生物合成的AgNPs主要呈球形,尺寸较小,范围在13 ~ 21 nm之间,在-23和-24 mV下高度稳定。本研究结果表明,利用油橄榄和阳光绿色合成的AgNPs具有明显的体外抗癌活性。绿色合成的进一步研究将有助于形成高质量的AgNPs,这些AgNPs在治疗疾病和对抗不良病原体方面具有广阔的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Optimization, Characterization, and Anticancer Potential of Silver Nanoparticles Biosynthesized Using <i>Olea europaea</i>.

Optimization, Characterization, and Anticancer Potential of Silver Nanoparticles Biosynthesized Using <i>Olea europaea</i>.

Optimization, Characterization, and Anticancer Potential of Silver Nanoparticles Biosynthesized Using <i>Olea europaea</i>.

Optimization, Characterization, and Anticancer Potential of Silver Nanoparticles Biosynthesized Using Olea europaea.

Green synthesis has attracted significant attention as an eco-friendly, low-cost, energy-efficient, and non-toxic method for preparing silver nanoparticles (AgNPs) for cancer therapy. This study optimized the green synthesis of AgNPs using Olea europaea extracts and evaluated their anticancer potential. The biosynthesized AgNPs were characterized using various methods, showing stable AgNPs with a desirable morphology and high yield, improving the properties of AgNPs for various medicinal applications. The biosynthesized AgNPs were predominantly spherical, with small sizes ranging from 13 to 21 nm and highly stable at -23 and -24 mV. The findings of this study suggest that green-synthesized AgNPs using Olea europaea and sunlight possess significant anticancer activity against cancer cells in vitro. Further investigation of green synthesis would help to form high-quality AgNPs that have promising potential in treating disease and fighting undesirable pathogens.

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来源期刊
International Journal of Biomaterials
International Journal of Biomaterials MATERIALS SCIENCE, BIOMATERIALS-
CiteScore
4.30
自引率
3.20%
发文量
50
审稿时长
21 weeks
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