病理学家在前列腺癌主动监测中的作用。

IF 0.1 4区医学 Q4 Medicine

Analytical and Quantitative Cytopathology and Histopathology Pub Date : 2015-02-01

Roberta Mazzucchelli, Andrea B Galosi, Matteo Santoni, Antonio Lopez-Beltran, Marina Scarpelli, Liang Cheng, Rodolfo Montironi

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引用次数: 0

摘要

主动监测(AS)是一种替代策略，旨在通过仅选择具有显著前列腺癌(PCa)肿瘤的患者进行立即治疗来减少过度治疗。对具有良好肿瘤特征的患者，应密切监测血清前列腺特异性抗原(PSA)水平和连续前列腺活检。此外，肿瘤进展的其他预测因素，如PSA倍增时间，可以在as治疗期间使用。AS是鉴定前列腺癌行为的分子生物标志物和开发新的治疗策略的绝佳机会。

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Role of the pathologist in active surveillance for prostate cancer.

Active surveillance (AS) is an alternative strategy that aims to minimize overtreatment by selecting only patients with significant prostate cancer (PCa) tumors for immediate treatment. Patients with favorable tumor characteristics are closely monitored using serum prostate-specific antigen (PSA) levels and serial biopsies of the prostate. In addition, other predictors of tumor progression, such as PSA doubling time, can be used during AS management. AS represents an excellent opportunity to identify molecular biomarkers of PCa behavior and to develop novel therapeutic strategies.

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来源期刊

Analytical and Quantitative Cytopathology and Histopathology CELL BIOLOGY-

自引率

0.00%

发文量

审稿时长

1 months

期刊介绍： AQCH is an Official Periodical of The International Academy of Cytology and the Italian Society of Urologic Pathology.