Wesley T O'Neal, Waqas Qureshi, Suzanne E Judd, Stephen P Glasser, Lama Ghazi, LeaVonne Pulley, Virginia J Howard, George Howard, Elsayed Z Soliman
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引用次数: 23
摘要
背景:感知应激与心房颤动(AF)之间的关系尚不清楚。目的:本研究的目的是探讨感知压力与af之间的关系。方法:共有25530名参与者(平均年龄65±9.4岁;女性占54%;来自中风的地理和种族差异原因(REGARDS)研究的41%黑人被纳入本分析。采用Logistic回归计算短版Cohen感知压力量表与房颤之间的比值比(OR)和95%置信区间(CI)。结果:在调整了人口统计学、心血管危险因素和潜在混杂因素的多变量分析中，发现房颤的患病率随着压力水平的升高而增加(无:OR = 1.0，参考;低应力:OR = 1.12, 95% CI = 0.98, 1.27;中度应力OR = 1.27, 95% CI = 1.11, 1.47;高应激:OR = 1.60, 95% CI = 1.39, 1.84)。结论:感知压力水平的增加与REGARDS中AF的流行有关。
Perceived Stress and Atrial Fibrillation: The REasons for Geographic and Racial Differences in Stroke Study.
Background: The association between perceived stress and atrial fibrillation (AF) remains unclear.
Purpose: The aim of this study was to examine the association between perceived stress and AF.
Methods: A total of 25,530 participants (mean age 65 ± 9.4 years; 54 % women; 41 % blacks) from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study were included in this analysis. Logistic regression was used to compute odds ratios (OR) and 95 % confidence intervals (CI) for the association between the short version of the Cohen Perceived Stress Scale and AF.
Results: In a multivariable analysis adjusted for demographics, cardiovascular risk factors, and potential confounders, the prevalence of AF was found to increase with higher levels of stress (none: OR = 1.0, referent; low stress: OR = 1.12, 95 % CI = 0.98, 1.27; moderate stress OR = 1.27, 95 % CI = 1.11, 1.47; high stress: OR = 1.60, 95 % CI = 1.39, 1.84).
Conclusion: Increasing levels of perceived stress are associated with prevalent AF in REGARDS.
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