正压治疗在心律失常和阻塞性睡眠呼吸暂停患者中的应用。

Q4 Medicine
Pneumologia Pub Date : 2015-01-01
Giorgiana Nicoleta Dediu, Stefan Dumitrache-Rujinski, Rizvan Lungu, Sabina Frunză, Camelia Diaconu, Daniela Bartoş, Miron Alexandru Bogdan
{"title":"正压治疗在心律失常和阻塞性睡眠呼吸暂停患者中的应用。","authors":"Giorgiana Nicoleta Dediu,&nbsp;Stefan Dumitrache-Rujinski,&nbsp;Rizvan Lungu,&nbsp;Sabina Frunză,&nbsp;Camelia Diaconu,&nbsp;Daniela Bartoş,&nbsp;Miron Alexandru Bogdan","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Positive pressure therapy (CPAP) in patients with cardiac arrhythmias and obstructive sleep apnea (OSAS) may have favorable effects by correcting intermittent hypoxemia and sympathetic activation.</p><p><strong>Objective: </strong>To assess the effect of CPAP added to pharmacological treatment in the rate control and prevention of arrhythmias recurrence in patients with OSA.</p><p><strong>Materials and methods: </strong>Prospective, interventional study study which included patients diagnosed with OSAS (cardiorespiratorypolygraphy, AHI>5/hour), and arrhythmias (ECG, Holter ECG), divided in two groups: group A (pharmacological therapy only) and group B (pharmacological therapy and CPAP). The patients were evaluated at enrollment (T0), at 3 and 6 months (T3 and T6) regarding the type, severity and recurrence of cardiac arrhythmias.</p><p><strong>Results: </strong>36 patients (31 men), mean age: 63.2 ± 12 years were enroled. In group A: 7 patients with ventricular extrasystoles, 8 with permanent atrial fibrillation, 1 patient with atrial flutter and 2 patients with paroxystic supraventricular tachycardia. In group B: 8 patients with ventricular extrasystoles, 5 with permanent atrial fibrillation, 2 patients with recurrent episodes of atrial fibrillation and 3 with paroxystic supraventricular tachycardia. A positive correlation (r: 0.74, p < 0.001) between Oxygen Desaturation Index and AHI was found. At T6, 12 patients from group B, and 18 from group A were evaluated. In group B, the mean heart rate in patients with atrial fibrillation was 69/min., lower than in group A (82/min.), no cases with recurrent atrial fibrillation were found, and more patients with class II Lown ventricular extrasystoles passed in class I Lown, compared to group A. In group B, heart rate statistically correlated with AHI (r: 0.53, p < 0.005).</p><p><strong>Conclusion: </strong>In patients with OSAS, adding CPAP to pharmacological therapy has favorable effects on preventing recurrences, heart rate control in patients with atrial fibrillation and in reducing frequency and/or severity of ventricular extrasystoles.</p>","PeriodicalId":20345,"journal":{"name":"Pneumologia","volume":"64 1","pages":"18-22"},"PeriodicalIF":0.0000,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Positive pressure therapy in patients with cardiac arrhythmias and obstructive sleep apnea.\",\"authors\":\"Giorgiana Nicoleta Dediu,&nbsp;Stefan Dumitrache-Rujinski,&nbsp;Rizvan Lungu,&nbsp;Sabina Frunză,&nbsp;Camelia Diaconu,&nbsp;Daniela Bartoş,&nbsp;Miron Alexandru Bogdan\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Positive pressure therapy (CPAP) in patients with cardiac arrhythmias and obstructive sleep apnea (OSAS) may have favorable effects by correcting intermittent hypoxemia and sympathetic activation.</p><p><strong>Objective: </strong>To assess the effect of CPAP added to pharmacological treatment in the rate control and prevention of arrhythmias recurrence in patients with OSA.</p><p><strong>Materials and methods: </strong>Prospective, interventional study study which included patients diagnosed with OSAS (cardiorespiratorypolygraphy, AHI>5/hour), and arrhythmias (ECG, Holter ECG), divided in two groups: group A (pharmacological therapy only) and group B (pharmacological therapy and CPAP). The patients were evaluated at enrollment (T0), at 3 and 6 months (T3 and T6) regarding the type, severity and recurrence of cardiac arrhythmias.</p><p><strong>Results: </strong>36 patients (31 men), mean age: 63.2 ± 12 years were enroled. In group A: 7 patients with ventricular extrasystoles, 8 with permanent atrial fibrillation, 1 patient with atrial flutter and 2 patients with paroxystic supraventricular tachycardia. In group B: 8 patients with ventricular extrasystoles, 5 with permanent atrial fibrillation, 2 patients with recurrent episodes of atrial fibrillation and 3 with paroxystic supraventricular tachycardia. A positive correlation (r: 0.74, p < 0.001) between Oxygen Desaturation Index and AHI was found. At T6, 12 patients from group B, and 18 from group A were evaluated. In group B, the mean heart rate in patients with atrial fibrillation was 69/min., lower than in group A (82/min.), no cases with recurrent atrial fibrillation were found, and more patients with class II Lown ventricular extrasystoles passed in class I Lown, compared to group A. In group B, heart rate statistically correlated with AHI (r: 0.53, p < 0.005).</p><p><strong>Conclusion: </strong>In patients with OSAS, adding CPAP to pharmacological therapy has favorable effects on preventing recurrences, heart rate control in patients with atrial fibrillation and in reducing frequency and/or severity of ventricular extrasystoles.</p>\",\"PeriodicalId\":20345,\"journal\":{\"name\":\"Pneumologia\",\"volume\":\"64 1\",\"pages\":\"18-22\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pneumologia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pneumologia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

摘要

背景:正压治疗(CPAP)对心律失常和阻塞性睡眠呼吸暂停(OSAS)患者可能具有纠正间歇性低氧血症和交感神经激活的有利效果。目的:评价CPAP联合药物治疗在OSA患者心律失常复发率控制和预防中的作用。材料与方法:前瞻性、介入性研究纳入诊断为OSAS(心肺造影,AHI>5/h)、心律失常(心电图、动态心电图)的患者,分为两组:A组(仅药物治疗)和B组(药物治疗+ CPAP)。在入组时(T0)、3个月和6个月时(T3和T6)评估患者心律失常的类型、严重程度和复发情况。结果:入选患者36例(男性31例),平均年龄63.2±12岁。A组:室性心动过速7例,永久性房颤8例,心房扑动1例,阵发性室上性心动过速2例。B组:室性心动过速8例,永久性房颤5例,反复房颤2例,阵发性室上性心动过速3例。氧去饱和指数与AHI呈正相关(r: 0.74, p < 0.001)。T6时,B组12例,A组18例进行评估。B组房颤患者的平均心率为69次/分。,低于A组(82/min),无房颤复发病例,ⅱ类low室性早搏通过ⅰ类low的患者多于A组。B组心率与AHI有统计学相关性(r: 0.53, p < 0.005)。结论:osa患者在药物治疗的基础上加用CPAP对预防房颤复发、控制房颤患者心率、降低室性早搏发生频率和/或严重程度均有良好效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Positive pressure therapy in patients with cardiac arrhythmias and obstructive sleep apnea.

Background: Positive pressure therapy (CPAP) in patients with cardiac arrhythmias and obstructive sleep apnea (OSAS) may have favorable effects by correcting intermittent hypoxemia and sympathetic activation.

Objective: To assess the effect of CPAP added to pharmacological treatment in the rate control and prevention of arrhythmias recurrence in patients with OSA.

Materials and methods: Prospective, interventional study study which included patients diagnosed with OSAS (cardiorespiratorypolygraphy, AHI>5/hour), and arrhythmias (ECG, Holter ECG), divided in two groups: group A (pharmacological therapy only) and group B (pharmacological therapy and CPAP). The patients were evaluated at enrollment (T0), at 3 and 6 months (T3 and T6) regarding the type, severity and recurrence of cardiac arrhythmias.

Results: 36 patients (31 men), mean age: 63.2 ± 12 years were enroled. In group A: 7 patients with ventricular extrasystoles, 8 with permanent atrial fibrillation, 1 patient with atrial flutter and 2 patients with paroxystic supraventricular tachycardia. In group B: 8 patients with ventricular extrasystoles, 5 with permanent atrial fibrillation, 2 patients with recurrent episodes of atrial fibrillation and 3 with paroxystic supraventricular tachycardia. A positive correlation (r: 0.74, p < 0.001) between Oxygen Desaturation Index and AHI was found. At T6, 12 patients from group B, and 18 from group A were evaluated. In group B, the mean heart rate in patients with atrial fibrillation was 69/min., lower than in group A (82/min.), no cases with recurrent atrial fibrillation were found, and more patients with class II Lown ventricular extrasystoles passed in class I Lown, compared to group A. In group B, heart rate statistically correlated with AHI (r: 0.53, p < 0.005).

Conclusion: In patients with OSAS, adding CPAP to pharmacological therapy has favorable effects on preventing recurrences, heart rate control in patients with atrial fibrillation and in reducing frequency and/or severity of ventricular extrasystoles.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Pneumologia
Pneumologia Medicine-Pulmonary and Respiratory Medicine
CiteScore
0.20
自引率
0.00%
发文量
10
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信