{"title":"一个n=1的病例报告,一个患有自闭症的孩子服用抗生素后病情有所好转,一位父亲试图了解这可能意味着什么。","authors":"John Rodakis","doi":"10.3402/mehd.v26.26382","DOIUrl":null,"url":null,"abstract":"<p><p>The author, a parent of a child with autism, describes an n=1 case in which his child's autism symptoms dramatically and rapidly improved following administration of a common antibiotic. The author asserts that this finding is not unusual in the autism population and that, when combined with prior recent medical research, suggests that a link between autism and the microbiome in some children is not just plausible, but in fact likely for some meaningful percentage of cases. The author argues for increased funding for a more thorough examination of links between autism and the microbiome and poses a series of questions to be further examined in future research. </p>","PeriodicalId":18568,"journal":{"name":"Microbial Ecology in Health and Disease","volume":"26 ","pages":"26382"},"PeriodicalIF":0.0000,"publicationDate":"2015-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/mehd.v26.26382","citationCount":"17","resultStr":"{\"title\":\"An n=1 case report of a child with autism improving on antibiotics and a father's quest to understand what it may mean.\",\"authors\":\"John Rodakis\",\"doi\":\"10.3402/mehd.v26.26382\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The author, a parent of a child with autism, describes an n=1 case in which his child's autism symptoms dramatically and rapidly improved following administration of a common antibiotic. The author asserts that this finding is not unusual in the autism population and that, when combined with prior recent medical research, suggests that a link between autism and the microbiome in some children is not just plausible, but in fact likely for some meaningful percentage of cases. The author argues for increased funding for a more thorough examination of links between autism and the microbiome and poses a series of questions to be further examined in future research. </p>\",\"PeriodicalId\":18568,\"journal\":{\"name\":\"Microbial Ecology in Health and Disease\",\"volume\":\"26 \",\"pages\":\"26382\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-03-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3402/mehd.v26.26382\",\"citationCount\":\"17\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Microbial Ecology in Health and Disease\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3402/mehd.v26.26382\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2015/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microbial Ecology in Health and Disease","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3402/mehd.v26.26382","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2015/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
An n=1 case report of a child with autism improving on antibiotics and a father's quest to understand what it may mean.
The author, a parent of a child with autism, describes an n=1 case in which his child's autism symptoms dramatically and rapidly improved following administration of a common antibiotic. The author asserts that this finding is not unusual in the autism population and that, when combined with prior recent medical research, suggests that a link between autism and the microbiome in some children is not just plausible, but in fact likely for some meaningful percentage of cases. The author argues for increased funding for a more thorough examination of links between autism and the microbiome and poses a series of questions to be further examined in future research.