食管癌:筛查、靶向治疗和管理的最新进展。

Q1 Environmental Science

Journal of Carcinogenesis Pub Date : 2014-10-30 eCollection Date: 2014-01-01 DOI:10.4103/1477-3163.143720

Puja Gaur, Min P Kim, Brian J Dunkin

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引用次数: 36

摘要

食管癌的发病率在世界范围内呈上升趋势，尽管胃肠道肿瘤领域的研究很积极，但生存率仍然很低。食管癌仍有许多有待确定的领域，包括开发一种有效的筛查工具，确定用于监测目的的良好肿瘤标志物，靶向食管癌干细胞和循环肿瘤细胞的方法，以及开发治疗早期疾病的微创方案。本章的目的是强调食管癌领域的一些最新进展和正在进行的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Esophageal cancer: Recent advances in screening, targeted therapy, and management.

The incidence of esophageal cancer remains on the rise worldwide and despite aggressive research in the field of gastrointestinal oncology, the survival remains poor. Much remains to be defined in esophageal cancer, including the development of an effective screening tool, identifying a good tumor marker for surveillance purposes, ways to target esophageal cancer stem cells as well as circulating tumor cells, and developing minimally invasive protocols to treat early-stage disease. The goal of this chapter is to highlight some of the recent advances and ongoing research in the field of esophageal cancer.

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来源期刊

Journal of Carcinogenesis Environmental Science-Health, Toxicology and Mutagenesis

CiteScore

7.50

自引率

0.00%

发文量

审稿时长

15 weeks

期刊介绍： Journal of Carcinogenesis considers manuscripts in many areas of carcinogenesis and Chemoprevention. Primary areas of interest to the journal include: physical and chemical carcinogenesis and mutagenesis; processes influencing or modulating carcinogenesis, such as DNA repair; genetics, nutrition, and metabolism of carcinogens; the mechanism of action of carcinogens and modulating agents; epidemiological studies; and, the formation, detection, identification, and quantification of environmental carcinogens. Manuscripts that contribute to the understanding of cancer prevention are especially encouraged for submission