多发性硬化症患者的皮肤纹特征。

IF 1.3
Neurosciences (Riyadh, Saudi Arabia) Pub Date : 2014-10-01
Vedat Sabanciogullari, Seyda Cevik, Kezban Karacan, Ertugrul Bolayir, Mehmet Cimen
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引用次数: 0

摘要

目的:研究多发性硬化症(MS)的皮肤纹特征,阐明其遗传易感性。方法:研究于2013年1月- 12月在土耳其西瓦斯Cumhuriyet大学医学院解剖系和神经内科进行。61名患者和62名健康成人的皮肤纹数据通过数字扫描仪传输到计算机环境中。使用ImageJ程序,计算atd、data、adt角度、a-b脊数、所有手指样本类型、脊数。结果:MS患者双手a-b脊计数及各指脊计数均升高,差异有统计学意义。多发性硬化症患者双手的数据角度也有统计学上的显著增加。相反,两组间在真皮嵴样本方面无统计学差异,两组中最常见的样本为尺袢。结论:皮肤纹样本分布的异常支持MS病因的遗传易感性。多发性硬化症易感个体可通过分析皮肤纹样来确定。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Dermatoglyphic features in patients with multiple sclerosis.

Dermatoglyphic features in patients with multiple sclerosis.

Dermatoglyphic features in patients with multiple sclerosis.

Objective: To examine dermatoglyphic features to clarify implicated genetic predisposition in the etiology of multiple sclerosis (MS).

Methods: The study was conducted between January and December 2013 in the Departments of Anatomy, and Neurology, Cumhuriyet University School of Medicine, Sivas, Turkey. The dermatoglyphic data of 61 patients, and a control group consisting of 62 healthy adults obtained with a digital scanner were transferred to a computer environment. The ImageJ program was used, and atd, dat, adt angles, a-b ridge count, sample types of all fingers, and ridge counts were calculated.

Results: In both hands of the patients with MS, the a-b ridge count and ridge counts in all fingers increased, and the differences in these values were statistically significant. There was also a statistically significant increase in the dat angle in both hands of the MS patients. On the contrary, there was no statistically significant difference between the groups in terms of dermal ridge samples, and the most frequent sample in both groups was the ulnar loop.

Conclusion: Aberrations in the distribution of dermatoglyphic samples support the genetic predisposition in MS etiology. Multiple sclerosis susceptible individuals may be determined by analyzing dermatoglyphic samples.

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