[慢性血栓栓塞性肺动脉高压的可操作性]。

Q4 Medicine
Pneumologia Pub Date : 2014-04-01
Tudor Constantinescu, Miron Alexandru Bogdan
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引用次数: 0

摘要

未标记:我们提出的情况下,86岁的男性患者诊断为慢性血栓栓塞性肺动脉高压(CTEPH)近端双侧肺动脉阻塞。病史包括全身性高血压、前列腺良性腺瘤、原位结肠腺癌,局部放疗治愈;既往无血栓栓塞性疾病史。检查包括通过超声心动图和右心导管对肺血流动力学和右心室功能进行详细分析,通过对比断层扫描对肺循环进行影像学评估,以及对左心、呼吸功能、神经系统状态、肝肾功能进行全面评估。新的结肠镜检查证实结肠癌没有复发。近端CTEPH的唯一治疗方法是肺动脉内膜切除术,这是一种非常复杂的外科手术,全世界只有少数中心可以使用。该病例在一个多学科会议上进行了讨论,手术指征基于运动耐量损伤、手术可达血栓、无合并症和患者知情同意。干预的限制被认为是极端年龄和肿瘤病史。该手术在timi oara心血管外科由Walter Klepetko教授和Marian Gappar教授进行,临床和血液动力学结果良好。我们介绍了术后的副作用和随访中最重要的功能参数。结论:所有诊断为CTEPH的患者应首先评估肺内膜切除术,如果没有发现其他明显的合并症,老年不应被视为绝对禁忌症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Operability in chronic thromboembolic pulmonary hypertension].

Unlabelled: We present the case of a 86-year-old male patient diagnosed with chronic thromboembolic pulmonary hypertension (CTEPH) with proximal bilateral obstructions of the pulmonary arteries. The history included systemic hypertension, benign prostate adenoma and in situ colonic adenocarcinoma, cured by local radiotherapy; no prior history of thromboembolic disease was noted. The work-up comprised of a detailed analysis of pulmonary hemodynamics and right ventricular function by echocardiography and right heart catheterization, imagistic evaluation of the pulmonary circulation by contrast tomography, but also a complete evaluation of the left heart, respiratory function, neurologic status, liver and kidney function. A new colonoscopy confirmed the absence of relapse of the colonic carcinoma. The only curative therapy in proximal CTEPH is pulmonary endarterectomy, a very complex surgical procedures available in only a few centres worldwide. The case was discussed in a multidisciplinary meeting and the indications for surgery were based on exercise tolerance impairment, surgically accessible thrombi, absence of comorbidities and patient informed consent. The limits for the intervention were considered the extreme age and oncological history. The procedure was performed in Cardiovascular surgical department Timişoara, by prof. dr. Walter Klepetko and prof. dr. Marian Gappar, with good clinical and hemodinamic outcome. We present the post surgical side effects and the most important functional parameters of the follow-up.

Conclusion: pulmonary endarterectomy should be evaluated initially in all patients diagnosed with CTEPH and the old age should not be considered an absolute contraindication if no other significant comorbidities are identified.

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来源期刊
Pneumologia
Pneumologia Medicine-Pulmonary and Respiratory Medicine
CiteScore
0.20
自引率
0.00%
发文量
10
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