老年腹膜癌的细胞减少手术和HIPEC治疗。

IF 1.6 Q4 ONCOLOGY
J D Spiliotis, E Halkia, V A Boumis, D T Vassiliadou, A Pagoulatou, E Efstathiou
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引用次数: 40

摘要

背景:腹膜癌减胞术联合腹腔热化疗是一种严谨的手术治疗方法,最适合年轻、体能状态良好的患者。我们评估了在围手术期精心护理下接受CRS和HIPEC治疗腹膜癌的老年患者的结果。方法:在过去的5年中,所有70岁或以上连续接受腹膜癌治疗的患者都被纳入研究对象。主要结局是围手术期发病率和死亡率。次要结局是无病生存期和总生存期。结果:从100例确诊为PC并在本中心接受CRS和HIPEC治疗的患者中,我们纳入了30例年龄在70岁及以上的患者,并将结果与70岁以下的患者进行比较。总发病率为50%,而70岁以下(NSS)组为41.5%。老年组的死亡率为3.3%,而年轻组(NSS)为1.43%。老年组的中位总生存期为30个月,而年轻组为38个月。结论:在选定的老年患者中,细胞减少手术和HIPEC治疗腹膜癌是安全的,且发病率可接受。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Cytoreductive surgery and HIPEC for peritoneal carcinomatosis in the elderly.

Cytoreductive surgery and HIPEC for peritoneal carcinomatosis in the elderly.

Background: The combined treatment of peritoneal carcinomatosis with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy is a rigorous surgical treatment, most suitable for young and good performance status patients. We evaluated the outcomes of elderly patients undergoing CRS and HIPEC for peritoneal carcinomatosis with careful perioperative care.

Methods: All consecutive patients 70 years of age or older who were treated for peritoneal carcinomatosis over the past five years were included. Primary outcomes were perioperative morbidity and mortality. Secondary outcomes were disease-free survival and overall survival.

Results: From a pool of 100 patients, with a diagnosis of PC who underwent CRS and HIPEC in our center, we have included 30 patients at an age of 70 years or older and the results were compared to the patients younger than 70 years. The total morbidity rate was 50% versus 41.5% in the group younger than 70 years (NSS).The mortality rate was 3.3% in the elderly group versus 1.43%in the younger group (NSS). Median overall survival was 30 months in the older group versus 38 months in the younger group.

Conclusion: Cytoreductive surgery and HIPEC for peritoneal carcinomatosis may be safely performed with acceptable morbidity in selected elderly patients.

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来源期刊
CiteScore
3.70
自引率
0.00%
发文量
5
审稿时长
20 weeks
期刊介绍: International Journal of Surgical Oncology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies in all areas of surgical oncology.
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