在新罕布什尔州和佛蒙特州的室内和室外空气污染与肺癌。

IF 1.1 4区 环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES
Chantel D Sloan, Angeline S Andrew, Joann F Gruber, Kevin M Mwenda, Jason H Moore, Tracy Onega, Margaret R Karagas, Xun Shi, Eric J Duell
{"title":"在新罕布什尔州和佛蒙特州的室内和室外空气污染与肺癌。","authors":"Chantel D Sloan,&nbsp;Angeline S Andrew,&nbsp;Joann F Gruber,&nbsp;Kevin M Mwenda,&nbsp;Jason H Moore,&nbsp;Tracy Onega,&nbsp;Margaret R Karagas,&nbsp;Xun Shi,&nbsp;Eric J Duell","doi":"10.1080/02772248.2012.659930","DOIUrl":null,"url":null,"abstract":"<p><p>Indoor and outdoor air pollution is known to contribute to increased lung cancer incidence. This study is the first to address the contribution of home heating fuel and geographical course particulate matter (PM<sub>10</sub>) concentrations to lung cancer rates in New Hampshire, U.S. First, Pearson correlation analysis and Geographically weighted regression were used to investigate spatial relationships between outdoor PM<sub>10</sub> and lung cancer rates. While the aforementioned analyses did not indicate a significant contribution of PM<sub>10</sub> to lung cancer in the state, there was a trend towards a significant association in the northern and southwestern regions of the state. Second, case-control data were used to estimate the contributions of indoor pollution and second hand smoke to risk of lung cancer with adjustment for confounders. Increased risk was found among those who used wood or coal to heat their homes for more than 10 winters before the age of 18, with a significant increase in risk per winter. Resulting data suggest that further investigation of the relationship between heating-related air pollution levels and lung cancer risk is needed.</p>","PeriodicalId":23122,"journal":{"name":"Toxicological and Environmental Chemistry","volume":"94 3","pages":""},"PeriodicalIF":1.1000,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/02772248.2012.659930","citationCount":"14","resultStr":"{\"title\":\"Indoor and Outdoor Air Pollution and Lung Cancer in New Hampshire and Vermont.\",\"authors\":\"Chantel D Sloan,&nbsp;Angeline S Andrew,&nbsp;Joann F Gruber,&nbsp;Kevin M Mwenda,&nbsp;Jason H Moore,&nbsp;Tracy Onega,&nbsp;Margaret R Karagas,&nbsp;Xun Shi,&nbsp;Eric J Duell\",\"doi\":\"10.1080/02772248.2012.659930\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Indoor and outdoor air pollution is known to contribute to increased lung cancer incidence. This study is the first to address the contribution of home heating fuel and geographical course particulate matter (PM<sub>10</sub>) concentrations to lung cancer rates in New Hampshire, U.S. First, Pearson correlation analysis and Geographically weighted regression were used to investigate spatial relationships between outdoor PM<sub>10</sub> and lung cancer rates. While the aforementioned analyses did not indicate a significant contribution of PM<sub>10</sub> to lung cancer in the state, there was a trend towards a significant association in the northern and southwestern regions of the state. Second, case-control data were used to estimate the contributions of indoor pollution and second hand smoke to risk of lung cancer with adjustment for confounders. Increased risk was found among those who used wood or coal to heat their homes for more than 10 winters before the age of 18, with a significant increase in risk per winter. Resulting data suggest that further investigation of the relationship between heating-related air pollution levels and lung cancer risk is needed.</p>\",\"PeriodicalId\":23122,\"journal\":{\"name\":\"Toxicological and Environmental Chemistry\",\"volume\":\"94 3\",\"pages\":\"\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2012-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1080/02772248.2012.659930\",\"citationCount\":\"14\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Toxicological and Environmental Chemistry\",\"FirstCategoryId\":\"93\",\"ListUrlMain\":\"https://doi.org/10.1080/02772248.2012.659930\",\"RegionNum\":4,\"RegionCategory\":\"环境科学与生态学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ENVIRONMENTAL SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Toxicological and Environmental Chemistry","FirstCategoryId":"93","ListUrlMain":"https://doi.org/10.1080/02772248.2012.659930","RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
引用次数: 14

摘要

众所周知,室内和室外空气污染会导致肺癌发病率增加。本研究首次探讨了美国新罕布什尔州家庭取暖燃料和地理过程中颗粒物(PM10)浓度对肺癌发病率的影响。首先,使用Pearson相关分析和地理加权回归研究了室外PM10与肺癌发病率之间的空间关系。虽然上述分析并未表明PM10对该州肺癌的重大贡献,但在该州的北部和西南部地区有一种显著关联的趋势。其次,使用病例对照数据来估计室内污染和二手烟对肺癌风险的贡献,并对混杂因素进行调整。在18岁之前使用木柴或煤炭取暖超过10个冬天的人,风险增加,每个冬天的风险都显著增加。由此得出的数据表明,需要进一步调查与供暖有关的空气污染水平与肺癌风险之间的关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Indoor and Outdoor Air Pollution and Lung Cancer in New Hampshire and Vermont.

Indoor and outdoor air pollution is known to contribute to increased lung cancer incidence. This study is the first to address the contribution of home heating fuel and geographical course particulate matter (PM10) concentrations to lung cancer rates in New Hampshire, U.S. First, Pearson correlation analysis and Geographically weighted regression were used to investigate spatial relationships between outdoor PM10 and lung cancer rates. While the aforementioned analyses did not indicate a significant contribution of PM10 to lung cancer in the state, there was a trend towards a significant association in the northern and southwestern regions of the state. Second, case-control data were used to estimate the contributions of indoor pollution and second hand smoke to risk of lung cancer with adjustment for confounders. Increased risk was found among those who used wood or coal to heat their homes for more than 10 winters before the age of 18, with a significant increase in risk per winter. Resulting data suggest that further investigation of the relationship between heating-related air pollution levels and lung cancer risk is needed.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Toxicological and Environmental Chemistry
Toxicological and Environmental Chemistry ENVIRONMENTAL SCIENCES-TOXICOLOGY
CiteScore
3.50
自引率
5.60%
发文量
0
期刊介绍: The journal is interdisciplinary in outlook, and manuscripts published in it cover all relevant areas: • inorganic chemistry – trace elements in food and the environment, metal complexes and chelates; • organic chemistry – environmental fate, chemical reactions, metabolites and secondary products, synthesis of standards and labelled materials; • physical chemistry – photochemistry, radiochemistry; • environmental chemistry – sources, fate, and sinks of xenochemicals, environmental partitioning and transport, degradation and deposition; • analytical chemistry – development and optimisation of analytical methods, instrumental and methodological advances, miniaturisation and automation; • biological chemistry – pharmacology and toxicology, uptake, metabolism, disposition of xenochemicals, structure-activity relationships, modes of action, ecotoxicological testing.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信