Balazs Oroszlany, Yoshinori Ikenaka, Aksorn Saengtiengchan, Mami Oguri, Shouta M M Nakayama, Mayumi Ishizuka
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引用次数: 0
摘要
爬行动物数量的减少在全世界都是一个令人担忧的趋势。然而,人们对外源性药物在这种减少中所起的作用知之甚少。本研究对红耳龟(Trachemys scripta elegans)、中国塘龟(Mauremys reevesii)和中国软壳龟(Pelodiscus sinensis) 3种淡水龟体内芘的代谢进行了研究。与其他脊椎动物相比,所有海龟的代谢物分布都很独特,主要代谢物是芘-1-硫酸盐。观察到的低II期酶代谢率提出了长期暴露影响的问题。
Metabolism of pyrene, a polycyclic aromatic hydrocarbon in freshwater turtles.
Reptile population decrease is an alarming trend all around the world. Yet little is known about the role of xenobiotics in this decrease. In this study, we investigated the metabolism of pyrene in three freshwater turtle species (Red-EARED sliders (Trachemys scripta elegans), Chinese pond turtles (Mauremys reevesii) and Chinese softshell turtles (Pelodiscus sinensis). Compared to other vertebrates, all turtles showed an unique metabolite distribution, pyrene-1-sulfate being the main metabolite. The observed low phase II enzyme metabolic rates raises the question of the effect of long-time exposure.
期刊介绍:
The Japanese Journal of Veterinary Research (JJVR) quarterly publishes peer-reviewed articles on all aspects of veterinary science. JJVR was originally published as a “University Journal” of veterinary science at Hokkaido University from more than 60 years ago. Currently, JJVR, is Japan’s leading scientific veterinary journal, and provides valuable information for the development of veterinary science by welcoming contributions from researchers worldwide.
JJVR offers online submission for Regular Papers, Short Communications, and Review Articles that are unpublished and not being considered for publication elsewhere. Research areas include:
Anatomy, Physiology, Biochemistry, Pharmacology, Microbiology, Infectious diseases, Parasitology, Laboratory Animal Science and Medicine, Internal Medicine, Surgery, Pathology, Theriogenology, Molecular Medicine, Public Health, Radiation Biology, Toxicology, Wildlife Biology and Medicine, Veterinary Hygiene, The other fields related to veterinary science.