糖尿病妇女子代心血管疾病风险:宫内环境的影响

Experimental Diabetes Research Pub Date : 2012-01-01 Epub Date: 2012-10-22 DOI:10.1155/2012/565160
Laura J Marco, Kate McCloskey, Peter J Vuillermin, David Burgner, Joanne Said, Anne-Louise Ponsonby
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引用次数: 57

摘要

妊娠期糖尿病的发病率在世界范围内不断增加,使大量婴儿在子宫内暴露于高血糖。这种暴露可能对后代的心血管健康产生长期的负面影响。评估新生儿期心血管状态的新方法现在是可用的,包括测量动脉内膜-中膜厚度和视网膜摄影。这些措施将使研究人员能够评估宫内暴露的相对影响,将其与遗传或出生后的环境因素区分开来。了解宫内环境的长期影响应有助于制定更有效的卫生政策和干预措施,以减少未来心血管疾病的负担。在产前阶段针对发育中的胎儿开展疾病预防可以优化社区健康结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cardiovascular disease risk in the offspring of diabetic women: the impact of the intrauterine environment.

The incidence of gestational diabetes is increasing worldwide, exposing large numbers of infants to hyperglycaemia whilst in utero. This exposure may have a long-term negative impact on the cardiovascular health of the offspring. Novel methods to assess cardiovascular status in the neonatal period are now available-including measuring arterial intima-media thickness and retinal photography. These measures will allow researchers to assess the relative impact of intrauterine exposures, distinguishing these from genetic or postnatal environmental factors. Understanding the long-term impact of the intrauterine environment should allow the development of more effective health policy and interventions to decrease the future burden of cardiovascular disease. Initiating disease prevention aimed at the developing fetus during the antenatal period may optimise community health outcomes.

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来源期刊
Experimental Diabetes Research
Experimental Diabetes Research 医学-内分泌学与代谢
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