Chunjie Wang, Jianguo Sun, Liuquan Sun, Jie Zhou, Dehui Wang
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引用次数: 15
摘要
本文讨论了仅观察当前状态数据时生存函数的非参数估计(McKeown和Jewell, Lifetime data Anal 16:15 -230, 2010;孙,间隔截割失效时间数据的统计分析,2006;孙与孙,史学33:85-96,2005)。在这种情况下,每个受试者只被观察一次,并且观察到感兴趣的失败时间小于或大于观察或审查时间。如果假定失效时间和观测时间是相互独立的,已经发展了几种方法来解决这个问题。在这里,我们将重点关注独立假设不成立的情况,并在copula模型框架下提出两个简单的估计过程。建议的估计允许人们在其他用途中进行敏感性分析或确定生存函数的形状。仿真研究表明,这两种方法效果良好,并将其应用于一个致瘤性研究的激励实例。
Nonparametric estimation of current status data with dependent censoring.
This paper discusses nonparametric estimation of a survival function when one observes only current status data (McKeown and Jewell, Lifetime Data Anal 16:215-230, 2010; Sun, The statistical analysis of interval-censored failure time data, 2006; Sun and Sun, Can J Stat 33:85-96, 2005). In this case, each subject is observed only once and the failure time of interest is observed to be either smaller or larger than the observation or censoring time. If the failure time and the observation time can be assumed to be independent, several methods have been developed for the problem. Here we will focus on the situation where the independent assumption does not hold and propose two simple estimation procedures under the copula model framework. The proposed estimates allow one to perform sensitivity analysis or identify the shape of a survival function among other uses. A simulation study performed indicates that the two methods work well and they are applied to a motivating example from a tumorigenicity study.
期刊介绍:
The objective of Lifetime Data Analysis is to advance and promote statistical science in the various applied fields that deal with lifetime data, including: Actuarial Science – Economics – Engineering Sciences – Environmental Sciences – Management Science – Medicine – Operations Research – Public Health – Social and Behavioral Sciences.