脑静脉血栓的误诊和治疗不当。

Thrombosis Pub Date : 2012-01-01 Epub Date: 2012-04-05 DOI:10.1155/2012/210676
P K Sasidharan
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引用次数: 46

摘要

脑静脉血栓形成(CVT)应考虑在鉴别诊断所有不明原因的中枢神经系统疾病突然发作。病因通常是几种常见的嗜血栓状态的亚临床形式一起发生,而不是典型的遗传和罕见的原因。由于临床表现和病因的异质性,漏诊。在一些所谓的特发性CVT患者中,营养缺乏和生活方式问题是更重要的发病因素,而不是单一的罕见原因。高怀疑指数是诊断的关键。临床技能必须微调,以诊断问题,并确定所有的病因。放射学对诊断至关重要,但仅依靠放射学会导致漏诊甚至误诊。过早进行实验室检查是不合适的,而忘记了通过研究患者的饮食、生活方式和环境来进行适当的临床评估。管理的成功在于找出所有的促成原因并纠正它们,几乎总是能产生出色的结果。基于病例系列的临床观察和单独分享这些信息是在诊断和管理方面达成共识的手段。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Cerebral vein thrombosis misdiagnosed and mismanaged.

Cerebral vein thrombosis misdiagnosed and mismanaged.

Cerebral vein thrombosis misdiagnosed and mismanaged.

Cerebral vein thrombosis misdiagnosed and mismanaged.

Cerebral venous thrombosis (CVT) should be considered in the differential diagnosis of all unexplained CNS disorders of sudden onset. Etiological factors are often subclinical forms of several common thrombophilic states occurring together, rather than the typical inherited and rare causes. Diagnosis is missed because of the heterogeneity in clinical presentation and etiological factors. In several patients with the so called idiopathic CVT nutritional deficiencies and lifestyle issues are more important factors in pathogenesis, rather than single rarer causes. High index of suspicion is the key to diagnosis. Clinical skill has to be fine tuned to diagnose the problem and to identify all the etiological factors. Radiology is essential for diagnosis but relying on radiology alone will lead to missing several cases and even erroneous diagnosis. It is inappropriate to proceed prematurely to laboratory investigations, forgetting proper clinical evaluation by studying diet, lifestyle, and environment of the patients. Success in managing lies in identifying all the contributory causes and correcting all of them giving excellent outcome almost always. Clinical observations based on case series and sharing of such information alone are the means to arrive at a consensus in diagnosis and management.

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